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Apoptosis

Apoptosis, also known as programed cell death, is a tightly controlled cellular process which is characterized by membrane blebbing, cell shrinkage, chromatin condensation, and DNA fragmentation.

Products for Apoptosis

  1. Cat.No. Product Name Information
  2. BCN5384 Atractyloside potassium salt Atractyloside potassium salt
  3. BCN5524 Betulinic acid Betulinic acid
  4. BCN1016 Capsaicin Prototypic vanilloid receptor agonist Capsaicin
  5. BCN1552 Cisplatin Potent pro-apoptotic anticancer agent; activates caspase-3 Cisplatin
  6. BCN4804 Deguelin Anticancer and antiviral agent; chemopreventive and pro-apoptotic Deguelin
  7. BCN2678 Embelin Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor Embelin
  8. BCN2318 Gambogic acid Apoptosis inducer. Activates caspases Gambogic acid
  9. BCN5650 Matrine Matrine
  10. BCN4037 Piplartine Induces apoptosis; depletes androgen receptors in prostate cancer cells Piplartine
  11. BCN2586 Plumbagin Induces p53 Ser10 phosphorylation; anticancer Plumbagin
  12. BCN3834 Streptozotocin DNA alkylator; antitumor and induces diabetes Streptozotocin
  13. BCC1125 Q-VD-OPh hydrate Cell-permeable, irreversible pan-caspase inhibitor Q-VD-OPh hydrate
  14. BCC1126 Z-VAD-FMK Cell-permeable, irreversible caspase inhibitor Z-VAD-FMK
  15. BCC1128 Boc-D-FMK Pan-caspase inhibitor Boc-D-FMK
  16. BCC1137 Z-DEVD-FMK Caspase-3 inhibitor Z-DEVD-FMK
  17. BCC1138 Z-VDVAD-FMK Caspase-2 inhibitor Z-VDVAD-FMK
  18. BCC1139 Z-WEHD-FMK Caspase 5 inhibitor,potent,cell-permeable and irreversible Z-WEHD-FMK
  19. BCC1140 Caspase-3/7 Inhibitor I Caspase-3/7 inhibitor Caspase-3/7 Inhibitor I
  20. BCC1143 Apoptosis Inhibitor Associate with caspase-3 inhibition Apoptosis Inhibitor
  21. BCC1153 Bendamustine HCl Cytostatic agent; exhibits DNA alkylating and purine analog properties Bendamustine HCl
  22. BCC1156 Nutlin-3b MDM2/p53 inhibitor Nutlin-3b
  23. BCC1272 ABT-263 (Navitoclax) Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w ABT-263 (Navitoclax)
  24. BCC1283 AT-406 (SM-406) IAP inhibitor AT-406 (SM-406)
  25. BCC1306 3,3'-Diindolylmethane Activates Chk2; induces G2/M cell cycle arrest 3,3'-Diindolylmethane
  26. BCC1375 AT-101 Downregulates Bcl-2 and Mcl-1; pro-apoptotic AT-101
  27. BCC1397 BAM7 Selective Bax activator; induces Bax-mediated apoptosis BAM7
  28. BCC1438 Brassinolide Plant growth regulator Brassinolide
  29. BCC1509 D609 Selective PC-PLC inhibitor D609
  30. BCC1675 kb NB 142-70 Inhibitor of protein kinase D,selective kb NB 142-70
  31. BCC1691 LCL161 Antagonist of IAPs inhibitor LCL161
  32. BCC1697 Lenalidomide hydrochloride TNF-α secretion inhibitor Lenalidomide hydrochloride
  33. BCC1793 Necrostatin 2 In vitro necroptosis inhibitor Necrostatin 2
  34. BCC1812 Nutlin-3a chiral MDM2 inhibitor, antiproliferative and antiproapoptotic Nutlin-3a chiral
  35. BCC1830 p53 and MDM2 proteins-interaction-inhibitor chiral P53 and MDM2 proteins-interaction-inhibitor p53 and MDM2 proteins-interaction-inhibitor chiral
  36. BCC1831 p53 and MDM2 proteins-interaction-inhibitor racemic p53 and MDM2 proteins-interaction-inhibitor racemic
  37. BCC1844 Pemetrexed disodium hemipenta hydrate Pemetrexed disodium hemipenta hydrate
  38. BCC1879 R1530 Multi-RTK inhibitor; inhibits angiogenesis R1530
  39. BCC1894 RG7112 MDM2 inhibitor, first clinical RG7112
  40. BCC1895 RG7388 MDM2 antagonist, oral, selective RG7388
  41. BCC1955 SMIP004 Apoptosis inducer;downre SMIP004
  42. BCC1961 SPK-601 Potent PC-PLC inhibitor,antimicrobial agent SPK-601
  43. BCC2012 Trabectedin Antitumour agent Trabectedin
  44. BCC2055 WEHI-539 Bcl-xL inhibitor,potent and selective WEHI-539
  45. BCC2066 YM-155 hydrochloride Potent survivin inhibitor YM-155 hydrochloride
  46. BCC2077 Necrostatin 2 racemate In vitro necroptosis inhibitor Necrostatin 2 racemate
  47. BCC2078 Necrostatin 2 S enantiomer In vitro necroptosis inhibitor Necrostatin 2 S enantiomer
  48. BCC2099 Apoptosis Activator 2 Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis Apoptosis Activator 2
  49. BCC2228 2-Methoxyestradiol (2-MeOE2) Apoptotic and antiangiogenic agent 2-Methoxyestradiol (2-MeOE2)
  50. BCC2234 Obatoclax mesylate (GX15-070) Potent Bcl-2 inhibitor Obatoclax mesylate (GX15-070)
  51. BCC2235 BM-1074 Bcl-2/Bcl-xL inhibitor,potent and selective BM-1074
  52. BCC2236 Sabutoclax pan-Bcl-2 inhibitor Sabutoclax
  53. BCC2237 Apogossypolone (ApoG2) Bcl-2 inhibitor,nonpeptidic small molecule Apogossypolone (ApoG2)
  54. BCC2238 RITA (NSC 652287) p53-MDM2 interaction inhibitor; antitumor RITA (NSC 652287)
  55. BCC2239 Tenovin-1 Activates p53 transcriptional activity Tenovin-1
  56. BCC2240 JNJ-26854165 (Serdemetan) P53 activator, blocking Mdm2-p53 interaction JNJ-26854165 (Serdemetan)
  57. BCC2241 Pifithrin-α (PFTα) p53 inhibitor; supresses self renewal of embryonic stem cells Pifithrin-α (PFTα)
  58. BCC2242 NSC 319726 Reactivator of mutant p53 NSC 319726
  59. BCC2243 NSC 207895 (XI-006) MDMX inhibitor,anti-cancer agent NSC 207895 (XI-006)
  60. BCC2245 Lenalidomide (CC-5013) Antineoplastic agent,inhibits angiogenesis Lenalidomide (CC-5013)
  61. BCC2246 Pomalidomide (CC-4047) Immunomodulator,antumor/anti-angiogenic Pomalidomide (CC-4047)
  62. BCC2247 Necrostatin-1 Novel inhibitor of non-apoptotic cell death (necroptosis) Necrostatin-1
  63. BCC2250 Birinapant (TL32711) Potent XIAP/cIAP1 antagonist Birinapant (TL32711)
  64. BCC2251 YM155 Survivin suppressant,apoptosis inhibitor YM155
  65. BCC2252 GDC-0152 IAP antagonist,potent amd samll-molecule GDC-0152
  66. BCC2254 Nutlin-3 MDM2 antagonist,inhibits MDM2-p53 interaction Nutlin-3
  67. BCC2255 NSC 66811 MDM2 inhibitor. Disrupts MDM2-p53 interaction NSC 66811
  68. BCC2257 TW-37 Bcl-2 inhibitor; induces apoptosis TW-37
  69. BCC2356 AZ 10417808 Selective non-peptide caspase-3 inhibitor AZ 10417808
  70. BCC2357 Ivachtin Caspase-3 inhibitor Ivachtin
  71. BCC2359 Ac-LEHD-AFC Fluorogenic caspase substrate Ac-LEHD-AFC
  72. BCC2360 PETCM Activator of caspase-3 PETCM
  73. BCC2383 R18 Inhibitor of 14.3.3 proteins R18
  74. BCC2384 2,3-DCPE hydrochloride Bcl-XL protein expression downregulator 2,3-DCPE hydrochloride
  75. BCC2385 Actinomycin D Inhibits RNA polymerase Actinomycin D
  76. BCC2386 C 75 Potent fatty acid synthase inhibitor; proapoptotic C 75
  77. BCC2387 CHM 1 Potent antitumor agent; inducer of apoptosis CHM 1
  78. BCC2388 Mitomycin C Used for MEF/STO feeder layer preparation in stem cell culture Mitomycin C
  79. BCC2389 NSC 687852 (b-AP15) Inhibitor of UCHL5 and USP14 NSC 687852 (b-AP15)
  80. BCC2390 Oncrasin 1 Proapoptotic agent Oncrasin 1
  81. BCC2392 Bax channel blocker Inhibitor of Bax-mediated mitochondrial cytochrome c release Bax channel blocker
  82. BCC2393 Bax inhibitor peptide P5 Bax inhibitor Bax inhibitor peptide P5
  83. BCC2394 Bax inhibitor peptide V5 Inhibitor of Bax-mediated apoptosis Bax inhibitor peptide V5
  84. BCC2395 Bax inhibitor peptide, negative control Negative control peptide for Bax inhibitor peptide V5 Bax inhibitor peptide, negative control
  85. BCC2396 iMAC2 MAC inhibitor iMAC2
  86. BCC2397 Muristerone A Stimulates Bcl-XL mRNA transcription; antiapoptotic Muristerone A
  87. BCC2399 Cesium chloride Potassium channel blocker; neuroprotective Cesium chloride
  88. BCC2400 DAPK Substrate Peptide Death associated protein kinase substrate (synthetic) DAPK Substrate Peptide
  89. BCC2401 GRI 977143 Selective LPA2 agonist; antiapoptotic GRI 977143
  90. BCC2402 Mdivi 1 Selective inhibitor of dynamin related GTPase; attentuates mitochondrial division Mdivi 1
  91. BCC2403 Melphalan DNA alkylating agent; cytotoxic and antineoplastic Melphalan
  92. BCC2404 NQDI 1 ASK1 inhibitor NQDI 1
  93. BCC2405 TLQP 21 VGF-derived peptide TLQP 21
  94. BCC2406 CP 31398 dihydrochloride p53-stabilizing agent CP 31398 dihydrochloride
  95. BCC2407 Cyclic Pifithrin-α hydrobromide p53 inhibitor Cyclic Pifithrin-α hydrobromide
  96. BCC2408 HLI 373 Hdm2 inhibitor; activates p53-dependent transcription HLI 373
  97. BCC2409 MIRA-1 Restores mutant p53 activity; proapoptotic MIRA-1
  98. BCC2410 NSC 146109 hydrochloride Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription NSC 146109 hydrochloride
  99. BCC2411 PhiKan 083 p53 stabilizing agent PhiKan 083
  100. BCC2412 Pifithrin-μ Inhibitor of p53-mitochondrial binding Pifithrin-μ
  101. BCC2413 PRIMA-1 Restores mutant p53 activity; induces apoptosis PRIMA-1

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