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Cell Cycle/Checkpoint

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.

Products for Cell Cycle/Checkpoint

  1. Cat.No. Product Name Information
  2. BCN5251 10-Deacetylbaccatin III 10-Deacetylbaccatin III
  3. BCN5341 7-Xylosyltaxol 7-Xylosyltaxol
  4. BCN6271 Colchicine Inhibitor of tubulin Colchicine
  5. BCN5342 Docetaxel Microtubule stabilizer Docetaxel
  6. BCN4650 Paclitaxel Promotes assembly and inhibits disassembly of microtubules Paclitaxel
  7. BCN5957 Podophyllotoxin Podophyllotoxin
  8. BCN2542 Vincristine sulfate Disrupts microtubules Vincristine sulfate
  9. BCC1050 10058-F4 Arrests cell cycle at G0/G1 10058-F4
  10. BCC1067 Zoledronic Acid Potent nitrogen-containing bisphosphonates Zoledronic Acid
  11. BCC1077 Rigosertib (ON-01910,Estybon) Plk1 inhibitor Rigosertib (ON-01910,Estybon)
  12. BCC1085 ABT-751 (E7010) Inhibitor of microtubule polymerization; antimitotic and antitumor ABT-751 (E7010)
  13. BCC1091 Epothilone A Microtubule stabilizing macrolide Epothilone A
  14. BCC1092 Epothilone B (EPO906, Patupilone) Microtubule stabilization agent; promotes tubulin polymerization Epothilone B (EPO906, Patupilone)
  15. BCC1105 Roscovitine (Seliciclib,CYC202) Potent, selective cyclin-dependent kinase inhibitor Roscovitine (Seliciclib,CYC202)
  16. BCC1113 LY2835219 CDK4/6 inhibitor,potent and selective LY2835219
  17. BCC1149 NSC 23766 Selective inhibitor of Rac1-GEF interaction; antioncogenic NSC 23766
  18. BCC1152 SNS-032 (BMS-387032) Potent cdk2, cdk7 and cdk9 inhibitor SNS-032 (BMS-387032)
  19. BCC1154 Nu 6027 ATR/CDK inhibitor, potent and selective Nu 6027
  20. BCC1207 VE-821 ATR kinase inhibitor VE-821
  21. BCC1307 360A G-quadruplex structures inhibitor 360A
  22. BCC1308 360A iodide G-quadruplex structures inhibitor 360A iodide
  23. BCC1368 ARRY-520 R enantiomer KSP inhibitor ARRY-520 R enantiomer
  24. BCC1376 AT7519 Hydrochloride Multi-CDK inhibitor AT7519 Hydrochloride
  25. BCC1377 AT7519 trifluoroacetate CDK/cyclin inhibitor AT7519 trifluoroacetate
  26. BCC1439 BS-181 CDK7 inhibitor,highly selective BS-181
  27. BCC1462 CCT241533 Potent Chk2 inhibitor CCT241533
  28. BCC1463 CCT241533 hydrochloride CHK2 kinase inhibitor, novel CCT241533 hydrochloride
  29. BCC1464 CDK inhibitor II CDK inhibitor II
  30. BCC1465 CDK9 inhibitor CDK9 inhibitor CDK9 inhibitor
  31. BCC1466 CDK9 inhibitor 2 CDK9 inhibitor 2
  32. BCC1474 CGP60474 Potent dual cdk1/cdk2 inhibitor CGP60474
  33. BCC1479 CHR-6494 Haspin inhibitor,potent ands selective CHR-6494
  34. BCC1503 CVT-313 Cdk2 inhibitor CVT-313
  35. BCC1510 D-64131 Tubulin polymerization inhibitor. Antitumor in vivo D-64131
  36. BCC1535 Docetaxel Trihydrate Depolymerisation of microtubules inhibitor Docetaxel Trihydrate
  37. BCC1577 Flavopiridol Pan-cdk inhibitor Flavopiridol
  38. BCC1606 GSK2606414 Potent and selective PERK inhibitor; orally bioavailable GSK2606414
  39. BCC1608 GSK-923295 CENP-E inhibitor,small-molecule GSK-923295
  40. BCC1614 GW843682X Selective inhibitor of PLK1 and PLK3 GW843682X
  41. BCC1615 H-1152 Rho-kinase inhibitor H-1152
  42. BCC1616 H-1152 dihydrochloride Selective Rho-kinase (ROCK) inhibitor H-1152 dihydrochloride
  43. BCC1722 LY2835219 free base CDK inhibitor LY2835219 free base
  44. BCC1735 Mc-MMAD Potent tubulin inhibitor Mc-MMAD
  45. BCC1774 MMAD Tubulin inhibitor,highly potent MMAD
  46. BCC1775 Monomethyl auristatin E Antimitotic agent Monomethyl auristatin E
  47. BCC1816 NVP-LCQ195 CDK1/CDK2/CDK5 inhibitor NVP-LCQ195
  48. BCC1853 PF-3758309 PAK4 inhibitor PF-3758309
  49. BCC1858 PHA-767491 Cdc7/cdk9 inhibitor, potent, ATP-competitive PHA-767491
  50. BCC1867 Poloxin PLK1 inhibitor Poloxin
  51. BCC1875 Pyridostatin Drug used for promoting growth arrest Pyridostatin
  52. BCC1896 RI-1 RAD51 inhibitor,cell-permeable RI-1
  53. BCC1936 SCH900776 S-isomer Checkpoint kinase(Chk)inhibitor SCH900776 S-isomer
  54. BCC2032 Vc-MMAD Potent tubulin inhibitor Vc-MMAD
  55. BCC2043 VO-Ohpic trihydrate PTEN inhibitor VO-Ohpic trihydrate
  56. BCC2064 Y-33075 Y-33075
  57. BCC2081 BI 2536 Plk1 inhibitor,potent and ATP-competitive BI 2536
  58. BCC2182 Aurora A Inhibitor I Potent and selective Aurora kinase A inhibitor Aurora A Inhibitor I
  59. BCC2391 ARRY 520 trifluoroacetate Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation ARRY 520 trifluoroacetate
  60. BCC2398 SU 9516 Potent cdk2 inhibitor SU 9516
  61. BCC2509 Ispinesib (SB-715992) High affinity and selective allosteric KSP inhibitor Ispinesib (SB-715992)
  62. BCC2517 HMN-214 Plk inhibitor,broad-spectrum anti-tumor agent HMN-214
  63. BCC2521 PHA-793887 Pan-Cdk inhibitor PHA-793887
  64. BCC2537 BS-181 HCl CDK7 inhibitor,highly selective BS-181 HCl
  65. BCC2541 AT7519 Multi-CDK inhibitor AT7519
  66. BCC2543 MK-1775 Wee1 kinase inhibtor,potent and ATP-competitive MK-1775
  67. BCC2555 AZD7762 Checkpoint kinase inhibitor,ATP competitive AZD7762
  68. BCC3665 ZCL278 Cdc42 inhibitor ZCL278
  69. BCC3680 PD 0332991 (Palbociclib) HCl CDK4/6 inhibitor,highly selective PD 0332991 (Palbociclib) HCl
  70. BCC3689 AZD-5438 Potent cyclin-dependent kinase (cdk) 1, 2 and 9 inhibitor AZD-5438
  71. BCC3698 Palbociclib (PD0332991) Isethionate CDK4/6 inhibitor,highly selective Palbociclib (PD0332991) Isethionate
  72. BCC3731 AZ3146 Potent and selective Mps1 inhibitor AZ3146
  73. BCC3741 BMS265246 Potent cdk1/2 inhibitor BMS265246
  74. BCC3750 CHIR-124 Chk1 inhibitor,novel and potent CHIR-124
  75. BCC3765 Dinaciclib (SCH727965) Potent CDK inhibitor Dinaciclib (SCH727965)
  76. BCC3788 GSK461364 Plk1 inhibitor GSK461364
  77. BCC3817 MK-8776 (SCH-900776) Chk1 inhibitor,potent and selective MK-8776 (SCH-900776)
  78. BCC3839 PHA-848125 CDK inhibitor,potent and ATP-competitive PHA-848125
  79. BCC3886 BI6727 (Volasertib) Plk inhibitor,highly potent BI6727 (Volasertib)
  80. BCC3887 Purvalanol B Cyclin-dependent kinase inhibitor Purvalanol B
  81. BCC3923 LY2603618 Chk1 inhibitor,highly selective LY2603618
  82. BCC3924 Deferasirox Oral iron chelator Deferasirox
  83. BCC3925 Flavopiridol hydrochloride Cyclin-dependent kinase inhibitor Flavopiridol hydrochloride
  84. BCC3926 LEE011 CDK4/6 inhibitor LEE011
  85. BCC3927 R547 CDK1/2/4 inhibitor,ATP-competitive R547
  86. BCC3928 WHI-P180 EGFR/Janus Kinase 3 inhibitor WHI-P180
  87. BCC3961 MLN0905 Potent PLK1 inhibitor MLN0905
  88. BCC3962 Ro3280 PLK1 inhibitor,potent and highly selective Ro3280
  89. BCC3986 THZ2 CDK7 inhibitor THZ2
  90. BCC3990 Senexin B CDK8/CDK19 inhibitor, highly potent, selective and orally available Senexin B
  91. BCC3994 MK-8745 Aurora A inhibitor,potent and selective MK-8745
  92. BCC4005 THZ1 Covalent CDK7 inhibitor,potent and selective THZ1
  93. BCC4007 Ro 3306 Cyclin-dependent kinase (cdk) 1 inhibitor Ro 3306
  94. BCC4039 XL413 hydrochloride Potent and selective Cdc7 inhibitor XL413 hydrochloride
  95. BCC4056 Dolastatin 10 Antitumor agent Dolastatin 10
  96. BCC4067 Rigosertib sodium Rigosertib sodium
  97. BCC4101 LEE011 hydrochloride CDK inhibitor LEE011 hydrochloride
  98. BCC4102 LEE011 succinate CDK inhibitor LEE011 succinate
  99. BCC4103 LEE011 succinate hydrate CDK inhibitor LEE011 succinate hydrate
  100. BCC4105 LY2606368 CHK1 inhibitor LY2606368
  101. BCC4151 Nemorubicin Doxorubicin analog,anticancer drug Nemorubicin

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