BCN3191BavachromeneBotanical source: The seeds of Psoralea corylifolia L.(CAS NO.:41743-38-8)
BCN5479TrilobatinTrilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd, Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope. Neuroprotective effects. Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells.(CAS NO.:4192-90-9)
BCN7223Pinocembrin chalconeBotanical source: The rhizomes of Boesenbergia pandurata.(CAS NO.:4197-97-1)
BCN4635DihydropashanoneBotanical source: The roots of Angelica pubescens(CAS NO.:41997-41-5)
BCN5482PashanoneBotanical source: The root of Miliusa sinensis(CAS NO.:42438-78-8)
BCN6475OkaninOkanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways.(CAS NO.:484-76-4)
BCN5592ButeinButein, isolated from Dalbergia odorifera T. Chen, is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator (STAC).(CAS NO.:487-52-5)
BCN5945IsoliquiritinIsoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like effects and antifungal activity.(CAS NO.:5041-81-6)
BCN3496Cochinchinenin ABotanical source: From Daemonorops draco Bl.(CAS NO.:221696-69-1)
BCN56472',4'-DihydroxychalconeBotanical source: The roots of Glycyrrhiza glabra L.(CAS NO.:1776-30-3)
BCN7232AsebogeninBotanical source: The leaves of Pieris japonica.(CAS NO.:520-42-3)
BCN4845PedicinBotanical source: The herbs of Fissistigma oldhamii(CAS NO.:521-51-7)
BCN3192IsobavachromeneBotanical source: The seeds of Psoralea corylifolia L.(CAS NO.:52801-22-6)
BCN6477MareinBotanical source: The herbs of Coreopsis maritima(CAS NO.:535-96-6)
BCN39864-O-MethylhelichrysetinBotanical source: The herbs of Cephalotaxus sinensis(CAS NO.:56121-44-9)
BCN5768XanthohumolValosin-containing protein (VCP) inhibitor; impairs autophagosome maturation,Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities.(CAS NO.:569-83-5)
BCN6429FlavanomareinBotanical source: The herbs of Laurentia atropurpurea(CAS NO.:577-38-8)
BCN6332Licochalcone ALicochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects.(CAS NO.:58749-22-7)
BCN6333Licochalcone BLicochalcone B is an extract from the root of Glycyrrhiza inflate. Licochalcone B inhibits amyloid β (Aβ42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ions.(CAS NO.:58749-23-8)
BCN4126PhlorizinPhlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.(CAS NO.:60-81-1)
BCN4128PhloretinPhloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Prunus mandshurica, has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively.Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation.(CAS NO.:60-82-2)
BCN4149HelichrysetinHelichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells.(CAS NO.:62014-87-3)
