Bavachromene

CAS# 41743-38-8

Bavachromene

Catalog No. BCN3191----Order now to get a substantial discount!

Product Name & Size Price Stock
Bavachromene: 5mg Please Inquire In Stock
Bavachromene: 10mg Please Inquire In Stock
Bavachromene: 20mg Please Inquire Please Inquire
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Quality Control of Bavachromene

Number of papers citing our products

Chemical structure

Bavachromene

3D structure

Chemical Properties of Bavachromene

Cas No. 41743-38-8 SDF Download SDF
PubChem ID 5321800 Appearance Yellow powder
Formula C20H18O4 M.Wt 322.4
Type of Compound Chalcones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E)-1-(7-hydroxy-2,2-dimethylchromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
SMILES CC1(C=CC2=CC(=C(C=C2O1)O)C(=O)C=CC3=CC=C(C=C3)O)C
Standard InChIKey LYPURLGLYLCBSU-VMPITWQZSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Bavachromene

The seeds of Psoralea corylifolia L.

Biological Activity of Bavachromene

Description1. Bavachromene exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro.
TargetsBACE

Bavachromene Dilution Calculator

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Bavachromene Molarity Calculator

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Preparing Stock Solutions of Bavachromene

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1017 mL 15.5087 mL 31.0174 mL 62.0347 mL 77.5434 mL
5 mM 0.6203 mL 3.1017 mL 6.2035 mL 12.4069 mL 15.5087 mL
10 mM 0.3102 mL 1.5509 mL 3.1017 mL 6.2035 mL 7.7543 mL
50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5509 mL
100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Bavachromene

In vitro BACE-1 inhibitory phenolic components from the seeds of Psoralea corylifolia.[Pubmed:18666047]

Planta Med. 2008 Sep;74(11):1405-8.

A new isoflavone, neocorylin ( 1) was isolated from the seeds extract of Psoralea corylifolia L. (Fabaceae), together with eight known constituents ( 2 - 9), i. e., bakuchiol ( 2), psoralen ( 3), Bavachromene ( 4), isoBavachromene ( 5), bavachalcone ( 6), isobavachalcone ( 7), 7,8-dihydro-8-(4-hydrophenyl)-2,2-dimethyl-2 H,6 H-[1,2- B:5,4- B']dipyran-6-one ( 8), and bavachinin ( 9). The structure of the new isoflavone 1 was elucidated as 7-hydroxy-3-[2-methyl-2-(4-methylpenten-3-yl)-2 H-chromen-6-yl]-4 H-chromen-4-one by spectroscopic analyses. Neocorylin ( 1) as well as related compounds 2, 4 - 6, 8 and 9 exhibited a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro.

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