Products with Precursors bioactivity

Cat.No. Product Name
BCN6255 Pregnenolone
Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively. Pregnenolone has memory-enhancing effects, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.
BCN6574 Orsellinic acid
1. Orsellinic acid is a novel benzoquinone ring precursor for antroquinonol and 4-acetylantroquinonol B, it formed from acetyl-coenzyme Q (CoQ) and malonyl-CoA via polyketide pathway. 2. Orsellinic acid can block platelet activating factor (PAF)-mediated neuronal apoptosis without affecting G-protein coupled receptor (PAFR)-mediated neuroprotection, it can effectively attenuate PAFR-independent neuronal apoptosis.
BCN6667 Preskimmianine
1. Preskimmianine is the biogenetic precursor of skimmianine. 2. Preskimmianine can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.
BCN6776 Tyramine
Tyramine is a major mutagen precursor in soy sauce, being convertible to a mutagen by nitrite; it is the biological precursor of octopamine, both compounds are independent neurotransmitters, acting through various G-protein coupled receptors, they are antagonistic modulators of behavior and metabolism.
BCN6795 (R)-Reticuline
1. (R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids.

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