Products with Precursors bioactivity

Cat.No. Product Name
BCN3254 (-)-Pinoresinol
1. Pinoresinol (PIN)can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. 2. (+)-Pinoresinol possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans. 3. Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, suggests that this could be a mechanism by which PIN reduces proliferation and induces differentiation on HL60 cells.
BCN3332 Lanosterol
1. Lanosterol induces mild depolarization of mitochondria and promotes autophagy. 2. Lanosterol is indicative of altered Lanosterol metabolism during PD pathogenesis. 3. 10 μM Lanosterol during IVM in medium without serum and bases on recombinant human chorionic gonadotrophin has a positive effect on maturation of prepubertal ewe oocytes.
BCN3802 Nerylacetate
Nerylacetate and 1,5-dienes geranyl acetate are catalyzed to the cis-2,5-bis(hydroxymethyl)tetrahydrofurans 3 and 4 by OsO4.
BCN3807 1-Phenylbutane-1,3-dione
The starting 1-phenylbutane-1,3-dione is used as key intermediate for the synthesis of several new thiophene and pyrazole derivatives.
BCN3817 Glucoraphanin
1. Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver. 2. Glucoraphanin can ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice. 3. Glucoraphanin and Glucoerucin effectively act as antagonists for the aryl hydrocarbon receptor, and this may contribute to their established chemoprevention potency. 4. Glucoraphanin has antioxidant activity, it has important effects on the reversion of fatty liver.

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