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Rauvovertine A

CAS# 2055073-75-9

Rauvovertine A

Catalog No. BCN7728----Order now to get a substantial discount!

Product Name & Size Price Stock
Rauvovertine A: 5mg $1150 In Stock
Rauvovertine A: 10mg Please Inquire In Stock
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Quality Control of Rauvovertine A

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Chemical structure

Rauvovertine A

3D structure

Chemical Properties of Rauvovertine A

Cas No. 2055073-75-9 SDF Download SDF
PubChem ID 134714911 Appearance Powder
Formula C19H22N2O3 M.Wt 326.38
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,13S,15S,19R,20R,21R)-19-methyl-18-oxa-1,11-diazahexacyclo[11.8.0.02,16.04,12.05,10.015,20]henicosa-4(12),5,7,9-tetraene-17,21-diol
SMILES CC1C2C3CC4C5=C(CC(C3C(O1)O)N4C2O)C6=CC=CC=C6N5
Standard InChIKey AWYNNQCKGSFTMD-UXCCTWNPSA-N
Standard InChI InChI=1S/C19H22N2O3/c1-8-15-11-7-14-17-10(9-4-2-3-5-12(9)20-17)6-13(21(14)18(15)22)16(11)19(23)24-8/h2-5,8,11,13-16,18-20,22-23H,6-7H2,1H3/t8-,11+,13+,14+,15+,16?,18-,19?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rauvovertine A

The stems of Rauvolfia verticillata.

Biological Activity of Rauvovertine A

Description1. Rauvovertine A shows cytotoxicity in vitro against human tumor cell lines.

Rauvovertine A Dilution Calculator

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Rauvovertine A Molarity Calculator

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Preparing Stock Solutions of Rauvovertine A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0639 mL 15.3196 mL 30.6391 mL 61.2783 mL 76.5978 mL
5 mM 0.6128 mL 3.0639 mL 6.1278 mL 12.2557 mL 15.3196 mL
10 mM 0.3064 mL 1.532 mL 3.0639 mL 6.1278 mL 7.6598 mL
50 mM 0.0613 mL 0.3064 mL 0.6128 mL 1.2256 mL 1.532 mL
100 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.6128 mL 0.766 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rauvovertine A

Hexacyclic monoterpenoid indole alkaloids from Rauvolfia verticillata.[Pubmed:26474672]

Fitoterapia. 2015 Dec;107:44-48.

Five new hexacyclic monoterpenoid indole alkaloids, Rauvovertine A (1), 17-epi-Rauvovertine A (2), rauvovertine B (3), 17-epi-rauvovertine B (4), and rauvovertine C (5) together with 17 known analogues were isolated from the stems of Rauvolfia verticillata. Compounds 1/2 and 3/4 were obtained as C-17 epimeric mixtures due to rapid hemiacetal tautomerism in solution. The structures of 1-5 were established by spectroscopic analysis and with the aid of molecular modeling. The new alkaloids were evaluated for their cytotoxicity in vitro against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.

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