PlatycodigeninCAS# 22327-82-8 |
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Chemical structure
3D structure
| Cas No. | 22327-82-8 | SDF | Download SDF |
| PubChem ID | 318775 | Appearance | Powder |
| Formula | C30H48O7 | M.Wt | 520.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,10,11-trihydroxy-9,9-bis(hydroxymethyl)-2,2,6a,6b,12a-pentamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | ||
| SMILES | CC1(CCC2(C(C1)C3=CCC4C(C3(CC2O)C)(CCC5C4(CC(C(C5(CO)CO)O)O)C)C)C(=O)O)C | ||
| Standard InChIKey | APTNOIWSCDBIAS-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C30H48O7/c1-25(2)10-11-30(24(36)37)18(12-25)17-6-7-20-26(3)13-19(33)23(35)29(15-31,16-32)21(26)8-9-27(20,4)28(17,5)14-22(30)34/h6,18-23,31-35H,7-16H2,1-5H3,(H,36,37) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Platycodon grandiflorus
| Description | 1. Platycodigenin has in vitro anti-proliferative activity against the HSC-T6 cell line. |
Platycodigenin Dilution Calculator
Platycodigenin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9205 mL | 9.6025 mL | 19.2049 mL | 38.4098 mL | 48.0123 mL |
| 5 mM | 0.3841 mL | 1.9205 mL | 3.841 mL | 7.682 mL | 9.6025 mL |
| 10 mM | 0.192 mL | 0.9602 mL | 1.9205 mL | 3.841 mL | 4.8012 mL |
| 50 mM | 0.0384 mL | 0.192 mL | 0.3841 mL | 0.7682 mL | 0.9602 mL |
| 100 mM | 0.0192 mL | 0.096 mL | 0.192 mL | 0.3841 mL | 0.4801 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells.[Pubmed:23519261]
Molecules. 2012 Dec 13;17(12):14899-907.
Two new oleanane-type triterpenoids, named platycodonoids A and B (1, 2), together with five known saponins, including platycodin D (3), deapioplatycodin D (4), 3-O-beta-D-glucopyranosyl polygalacic acid (5), 3-O-beta-D-glucopyranosyl Platycodigenin (6) and polygalacin D (7), were isolated from the roots of Platycodon grandiflorum. On the basis of spectral data and chemical evidence, the structures of the new compounds were elucidated as 2beta,3beta,23,24-tetrahydroxy-28-nor-olean-12-en-16-one (1) and 2beta,3beta,23,24- tetrahydroxy-28-nor-olean-12-en-16-one-3-O-beta-D-glucopyranoside (2). Compounds 1-7 were evaluated for their in vitro anti-proliferative activity against the HSC-T6 cell line.
Platicodigenin isolated from platycodon grandiflorum.
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