NithiamideCAS# 140-40-9 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 140-40-9 | SDF | Download SDF |
| PubChem ID | 8798 | Appearance | Powder |
| Formula | C5H5N3O3S | M.Wt | 187.18 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | CL-5279; Aminitrozole | ||
| Solubility | DMSO : 100 mg/mL (534.25 mM; Need ultrasonic) | ||
| Chemical Name | N-(5-nitro-1,3-thiazol-2-yl)acetamide | ||
| SMILES | CC(=O)NC1=NC=C(S1)[N+](=O)[O-] | ||
| Standard InChIKey | UJRRDDHEMZLWFI-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C5H5N3O3S/c1-3(9)7-5-6-2-4(12-5)8(10)11/h2H,1H3,(H,6,7,9) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Nithiamide is a non-5-nitroimidazole drugs, is a antibiotic used in veterinary. |
Nithiamide Dilution Calculator
Nithiamide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.3425 mL | 26.7123 mL | 53.4245 mL | 106.849 mL | 133.5613 mL |
| 5 mM | 1.0685 mL | 5.3425 mL | 10.6849 mL | 21.3698 mL | 26.7123 mL |
| 10 mM | 0.5342 mL | 2.6712 mL | 5.3425 mL | 10.6849 mL | 13.3561 mL |
| 50 mM | 0.1068 mL | 0.5342 mL | 1.0685 mL | 2.137 mL | 2.6712 mL |
| 100 mM | 0.0534 mL | 0.2671 mL | 0.5342 mL | 1.0685 mL | 1.3356 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Nithiamide is a non-5-nitroimidazole drugs.
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Efficacy of nithiamide in preventing and treating swine dysentery in experimentally inoculated pigs.[Pubmed:879561]
Am J Vet Res. 1977 May;38(5):627-31.
In a series of experiments, weanling pigs (12 to 18 kg av weight) were inoculated by means of feed with scrapings and contents of dysenteric colons. Mucohemorrhagic diarrhea developed in 97% of the infected, nonmedicated pigs, and 80% of these pigs died. Prophylactic feed medication with Nithiamide at dose levels of 600, 300, or 150 ppm beginning 2 days before inoculation to 28 days after inoculation prevented the development of swine dysentery and permitted performance equal to that of the noninfected nonmedicated pigs. Morbidity and mortality were reduced by medication with 100 ppm of Nithiamide but these were not influenced by medication with 50 ppm. Therapeutic feed medication with Nithiamide at a dose level of 150 ppm beginning the day after diarrhea first occurred was not effective. A single oral dose of Nithiamide (25 mg/kg of body weight), when diarrhea first occurred in each pig, produced rapid remission of the signs of dysentery; relapses occurred 1 to 2 weeks later, however, and mortality followed. The combination of oral dosage and feed medication was highly effective in treating dysentery, preventing its recurrence, and maintaining performance.
Nithiamide is a non-5-nitroimidazole drugs, is a antibiotic used in veterinary.
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