Liriope muscari baily saponins CCAS# 87480-46-4 |
- Ophiopogonin D'
Catalog No.:BCN2645
CAS No.:65604-80-0
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 87480-46-4 | SDF | Download SDF |
| PubChem ID | 14682468 | Appearance | Powder |
| Formula | C44H70O14 | M.Wt | 823.0 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-[5-hydroxy-6-(hydroxymethyl)-2-(5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl)oxy-4-(3,4,5-trihydroxyoxan-2-yl)oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol | ||
| SMILES | CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)OC8C(C(C(CO8)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1 | ||
| Standard InChIKey | DQYACEDUQHWXQZ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C44H70O16/c1-19-8-13-44(54-17-19)20(2)30-28(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)56-41-38(59-40-36(52)34(50)31(47)21(3)55-40)37(33(49)29(16-45)57-41)58-39-35(51)32(48)27(46)18-53-39/h6,19-21,23-41,45-52H,7-18H2,1-5H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF. |
| Targets | IL Receptor |
| In vivo | Anti-thrombotic activity of DT-13, a saponin isolated from the root tuber of Liriope muscari.[Pubmed: 23833374]Indian J Pharmacol. 2013 May-Jun; 45(3): 283–285.To investigate the anti-thrombotic activity of DT-13(Liriope muscari baily saponins C) in experimental animal models. |
| Structure Identification | 《Pharmaceutical Care and Research》 2007-06Preparation of liriope muscari baily saponins C solid lipid nanoparticles[Reference: WebLink]To prepare Liriope muscari baily saponins C solid lipid nanoparticles(DT-13-SLN) and to assess their physico-chemical characteristics. |
Liriope muscari baily saponins C Dilution Calculator
Liriope muscari baily saponins C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.2151 mL | 6.0753 mL | 12.1507 mL | 24.3013 mL | 30.3767 mL |
| 5 mM | 0.243 mL | 1.2151 mL | 2.4301 mL | 4.8603 mL | 6.0753 mL |
| 10 mM | 0.1215 mL | 0.6075 mL | 1.2151 mL | 2.4301 mL | 3.0377 mL |
| 50 mM | 0.0243 mL | 0.1215 mL | 0.243 mL | 0.486 mL | 0.6075 mL |
| 100 mM | 0.0122 mL | 0.0608 mL | 0.1215 mL | 0.243 mL | 0.3038 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Anti-thrombotic activity of DT-13, a saponin isolated from the root tuber of Liriope muscari.[Pubmed:23833374]
Indian J Pharmacol. 2013 May-Jun;45(3):283-5.
OBJECTIVE: To investigate the anti-thrombotic activity of DT-13 in experimental animal models. MATERIALS AND METHODS: The anti-thrombotic activity of DT-13 was evaluated by measuring the thrombus induced by inferior vena cava (IVC) ligation in mice and rats. The anti-thrombotic mechanism of DT-13 was investigated by assessing the mRNA expression levels of interleukin-6 (IL-6) and tissue factor (TF) in rat IVC tissue around thrombus. RESULTS: DT-13 markedly inhibited thrombosis induced by IVC ligation for 6 h in mice (2.0 and 4.0 mg/kg, p.o.) and for 18 h in rats (1.4 mg/kg, p.o.). Furthermore, DT-13 down-regulated the increased mRNA expression levels of IL-6 and TF in rats. CONCLUSIONS: DT-13 has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.
