Garcinone ECAS# 112649-21-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 112649-21-5 | SDF | Download SDF |
| PubChem ID | 10298511 | Appearance | Yellow powder |
| Formula | C28H32O6 | M.Wt | 464.6 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2,3,6,8-tetrahydroxy-1,4,7-tris(3-methylbut-2-enyl)xanthen-9-one | ||
| SMILES | CC(=CCC1=C(C=C2C(=C1O)C(=O)C3=C(C(=C(C(=C3O2)CC=C(C)C)O)O)CC=C(C)C)O)C | ||
| Standard InChIKey | WVJYEKGQSBGNRP-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C28H32O6/c1-14(2)7-10-17-20(29)13-21-23(24(17)30)27(33)22-18(11-8-15(3)4)25(31)26(32)19(28(22)34-21)12-9-16(5)6/h7-9,13,29-32H,10-12H2,1-6H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The fruits of Garcinia mangostana
| Description | 1. Garcinone E is active constituents in the anticomplement assay used. 2. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. 3. Garcinone E has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer. |
| Targets | Antifection |
Garcinone E Dilution Calculator
Garcinone E Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1524 mL | 10.7619 mL | 21.5239 mL | 43.0478 mL | 53.8097 mL |
| 5 mM | 0.4305 mL | 2.1524 mL | 4.3048 mL | 8.6096 mL | 10.7619 mL |
| 10 mM | 0.2152 mL | 1.0762 mL | 2.1524 mL | 4.3048 mL | 5.381 mL |
| 50 mM | 0.043 mL | 0.2152 mL | 0.4305 mL | 0.861 mL | 1.0762 mL |
| 100 mM | 0.0215 mL | 0.1076 mL | 0.2152 mL | 0.4305 mL | 0.5381 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Xanthone constituents of the fruits of Garcinia mangostana with anticomplement activity.[Pubmed:20878711]
Phytother Res. 2010 Oct;24(10):1575-7.
Phytochemical investigation of a chloroform-soluble fraction of the freeze-dried fruits of Garcinia mangostana (Clusiaceace) with anticomplement activity in the classical pathway led to the identification of five known xanthones. The structures of these compounds were confirmed by interpretation of NMR and MS spectroscopic data. Of the isolates obtained, 1-isomangostin and Garcinone E were found to be active constituents in the anticomplement assay used.
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