AsatoneCAS# 38451-63-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 38451-63-7 | SDF | Download SDF |
| PubChem ID | 431129 | Appearance | Cryst. |
| Formula | C24H32O8 | M.Wt | 448.50 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3,3,5,8,10,10-hexamethoxy-7,11-bis(prop-2-enyl)tricyclo[6.2.2.02,7]dodeca-5,11-diene-4,9-dione | ||
| SMILES | COC1=CC2(C(C3C(=CC2(C(=O)C3(OC)OC)OC)CC=C)C(C1=O)(OC)OC)CC=C | ||
| Standard InChIKey | XBKKBTPYPCCCKA-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C24H32O8/c1-9-11-15-13-22(28-4)20(26)23(29-5,30-6)17(15)18-21(22,12-10-2)14-16(27-3)19(25)24(18,31-7)32-8/h9-10,13-14,17-18H,1-2,11-12H2,3-8H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The whole plant of Asarum macranthum Hook.f.
| Description | 1. Asatone has antifeedant activity. |
Asatone Dilution Calculator
Asatone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2297 mL | 11.1483 mL | 22.2965 mL | 44.5931 mL | 55.7414 mL |
| 5 mM | 0.4459 mL | 2.2297 mL | 4.4593 mL | 8.9186 mL | 11.1483 mL |
| 10 mM | 0.223 mL | 1.1148 mL | 2.2297 mL | 4.4593 mL | 5.5741 mL |
| 50 mM | 0.0446 mL | 0.223 mL | 0.4459 mL | 0.8919 mL | 1.1148 mL |
| 100 mM | 0.0223 mL | 0.1115 mL | 0.223 mL | 0.4459 mL | 0.5574 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A neolignoid feeding deterrent againstLuehdorfia puziloi larvae (lepidoptera: Papilionidae) fromHeterotropa aspera, a host plant of sibling species,L. japonica.[Pubmed:24233682]
J Chem Ecol. 1995 Oct;21(10):1541-8.
A feeding deterrent against larvae of a papilionid butterfly,Luehdorfia puziloi (Parnassiinae), a specialist onAsiasarum plants (Aristolochiaceae), was isolated from another aristolochiaceous plant,Heterotropa aspera. Antifeedant activity was exhibited by then-hexane-soluble fraction that proved to contain at least two active components. One of the deterrents was identified as a neolignan compound, Asatone. The concentration of Asatone inH. aspera was estimated at approximately 225 ppm, and larval feeding ofL. puziloi was significantly deterred at concentrations over 90 ppm. By contrast, Asatone was not detectable (< 1 ppm, if any) in its host plant,Asiasarum sieboldii.
Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways.
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