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10-Hydroxyscandine

10-Hydroxyscandine

Catalog No. BCN6078
Size Price Stock
20mg $298 In stock
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Quality Control of 10-Hydroxyscandine

Chemical structure

10-Hydroxyscandine

10-Hydroxyscandine Dilution Calculator

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Chemical Properties of 10-Hydroxyscandine

Cas No. 119188-47-5 SDF Download SDF
SMILES COC(=O)[C@]12C[C@@]3(C=CCN4[C@@H]3[C@@]1(CC4)c5cc(ccc5NC2=O)O)C=C
Standard InChIKey LGEFXJCPQAMQOD-VRXWPRPYSA-N
Standard InChI InChI=1S/C21H22N2O4/c1-3-19-7-4-9-23-10-8-20(16(19)23)14-11-13(24)5-6-15(14)22-17(25)21(20,12-19)18(26)27-2/h3-7,11,16,24H,1,8-10,12H2,2H3,(H,22,25)/t16-,19-,20+,21+/m0/s1
Type of Compound Alkaloids Appearance Powder
Formula C21H22N2O4 M.Wt 366.4
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 10-Hydroxyscandine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7293 mL 13.6463 mL 27.2926 mL 54.5852 mL 68.2314 mL
5 mM 0.5459 mL 2.7293 mL 5.4585 mL 10.917 mL 13.6463 mL
10 mM 0.2729 mL 1.3646 mL 2.7293 mL 5.4585 mL 6.8231 mL
50 mM 0.0546 mL 0.2729 mL 0.5459 mL 1.0917 mL 1.3646 mL
100 mM 0.0273 mL 0.1365 mL 0.2729 mL 0.5459 mL 0.6823 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 10-Hydroxyscandine

This product is isolated and purified from the stem bark of Melodinus tenuicaudatus

References on 10-Hydroxyscandine

Alkaloid-fullerene systems through photocycloaddition reactions.[Pubmed: 10864768]


The photocycloaddition of tertiary amines to ¿60fullerene (C(60)) is an interesting and useful reaction. We wished to extend the applications of this type of reaction through an investigation of the photoaddition of alkaloids to C(60) for the purpose of synthesizing novel and complex photoadducts that are difficult to obtain by usual methods. Irradiation of tazettine (2) or gramine (3) with C(60) in toluene leads to formation of one monoadduct (6 or 7), whereas scandine (1a) or 10-Hydroxyscandine (1b) reacts with C(60) photochemically to give two products, the expected ¿6,6 monoadduct (5a, 5b) and a new type of monoadduct with a bis-¿6, 6 closed structure (4a, 4b).

Study on the Alkaloids of Melodinus tenuicaudatus.[Pubmed: 17265274 ]


Fourteen alkaloids were isolated from the stem bark of MELODINUS TENUICAUDATUS Tsiang et P. T. Li. Eleven of them were identified as known alkaloids, namely, scandine ( 2), Delta (14)-eburnamine ( 4), vindolinine N(b)-oxide ( 5), 11-methoxytabersonine ( 6), vindolinine ( 7), EPI-vindolinine N(b)-oxide ( 8), hazuntine ( 9), compactinervine ( 10), 11-hydroxytabersonine ( 11), Delta (14)-vincine ( 12), and normacusine B ( 14). Two alkaloids were new: 10-Hydroxyscandine ( 1), and the dimer, tenuicausine ( 3); their structures were elucidated by spectroscopic and chemical methods. One alkaloid ( 13) occurring in trace amounts, could not be identified.

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