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1-Deacetylnimbolinin B

1-Deacetylnimbolinin B

Catalog No. BCN4313
Size Price Stock
20mg $298 In stock
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Quality Control of 1-Deacetylnimbolinin B

Chemical structure

1-Deacetylnimbolinin B

1-Deacetylnimbolinin B Dilution Calculator

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1-Deacetylnimbolinin B Molarity Calculator



Chemical Properties of 1-Deacetylnimbolinin B

Cas No. 76689-98-0 SDF Download SDF
Standard InChI InChI=1S/C33H44O9/c1-8-16(2)30(37)42-29-27-28-31(5,15-39-27)24(40-18(4)34)13-23(35)32(28,6)22-12-25(36)41-21-11-20(19-9-10-38-14-19)17(3)26(21)33(22,29)7/h8-10,14,20-25,27-29,35-36H,11-13,15H2,1-7H3/b16-8+/t20-,21+,22-,23+,24-,25-,27-,28+,29-,31-,32+,33-/m1/s1
Type of Compound Triterpenoids Appearance Powder
Formula C33H44O9 M.Wt 584.7
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1-Deacetylnimbolinin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7103 mL 8.5514 mL 17.1028 mL 34.2056 mL 42.757 mL
5 mM 0.3421 mL 1.7103 mL 3.4206 mL 6.8411 mL 8.5514 mL
10 mM 0.171 mL 0.8551 mL 1.7103 mL 3.4206 mL 4.2757 mL
50 mM 0.0342 mL 0.171 mL 0.3421 mL 0.6841 mL 0.8551 mL
100 mM 0.0171 mL 0.0855 mL 0.171 mL 0.3421 mL 0.4276 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1-Deacetylnimbolinin B

This product is isolated and purified from the seeds of Melia toosendan Sieb. et Zucc.

References on 1-Deacetylnimbolinin B

Vitamin B 12 deficiency may coexist with endocrine causes of hyperpigmentation.[Pubmed: 29025167]

"Why Do I Feel This Pain?" B-Mode and Power Doppler Ultrasound Found the Answer: A Neurovascular Conflict.[Pubmed: 29025023]

Unprecedented Sensitivity in a Probe for Detection and Imaging of Cathepsin B: Chemiluminescence Microscopy Cell Images of Natively-Expressed Enzyme.[Pubmed: 29024539]

Until recently, chemiluminescence cell images could be obtained only using luciferase-activated probes. Moreover, chemiluminescence microscopy cell-imaging was never demonstrated for natively expressed enzymes like cathepsin B. Here we describe the design synthesis and evaluation of the first chemiluminescence probe for detection and imaging of cathepsin B. The probe activation mechanism relies on the release of a dioxetane intermediate, which undergoes chemiexcitation to emit green light with high efficiency under physiological conditions. Using the probe, we obtained clear images of cancerous leukemia and colon cells. This is the first demonstration of chemiluminescence cell images obtained by a probe for a natively-expressed endogenous enzyme. We anticipate that the concept presented in this study will be broadly used to develop analogous probes for other important proteases relevant to biomolecular processes.

A novel HLA-B allele, HLA-B*35:348, was identified by sequencing-based typing.[Pubmed: 29024525]

HLA-B*35:348 has one nucleotide substitution, c.817G>C (GTG→CTG at codon 248) compared to B*35:01:01:01.


1-Deacetylnimbolinin B ,76689-98-0,Nature Products, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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