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Catalog No. BCN3101
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20mg $298 In stock
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Quality Control of 1-Acetyl-beta-carboline

Chemical structure


Biological Activity of 1-Acetyl-beta-carboline

1. Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.

1-Acetyl-beta-carboline Dilution Calculator

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1-Acetyl-beta-carboline Molarity Calculator



Chemical Properties of 1-Acetyl-beta-carboline

Cas No. 50892-83-6 SDF Download SDF
SMILES CC(=O)c1c2c(ccn1)c3ccccc3[nH]2
Standard InChI InChI=1S/C13H10N2O/c1-8(16)12-13-10(6-7-14-12)9-4-2-3-5-11(9)15-13/h2-7,15H,1H3
Type of Compound Alkaloids Appearance Cryst
Formula C13H10N2O M.Wt 210.2
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 1-Acetyl-beta-carboline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7574 mL 23.7869 mL 47.5737 mL 95.1475 mL 118.9343 mL
5 mM 0.9515 mL 4.7574 mL 9.5147 mL 19.0295 mL 23.7869 mL
10 mM 0.4757 mL 2.3787 mL 4.7574 mL 9.5147 mL 11.8934 mL
50 mM 0.0951 mL 0.4757 mL 0.9515 mL 1.9029 mL 2.3787 mL
100 mM 0.0476 mL 0.2379 mL 0.4757 mL 0.9515 mL 1.1893 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 1-Acetyl-beta-carboline

This product is isolated and purified from the barks of Picrasma quassioides

References on 1-Acetyl-beta-carboline

The synergistic antibacterial activity of 1-acetyl-beta-carboline and beta-lactams against methicillin-resistant Staphylococcus aureus (MRSA).[Pubmed: 20372018]

1-Acetyl-beta-carboline was isolated as an anti-MRSA agent from the fermentation broth of a marine actinomycete isolated from marine sediment. The producing strain was identified to be Streptomyces sp. by phylogenetic analysis of the 16S rRNA gene sequence. The anti-MRSA agent was isolated by bioactivity-guided fractionation of the culture extract by solvent partitioning, ODS open flash chromatography, and purification with a reversed-phase HPLC. Its structure was elucidated by extensive 2D NMR and mass spectral analyses. Combination of 1-Acetyl-beta-carboline with ampicillin exhibited synergistic antibacterial activity against MRSA.


1-Acetyl-beta-carboline ,50892-83-6,Nature Products, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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