1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-oneCAS# 332371-82-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 332371-82-1 | SDF | Download SDF |
| PubChem ID | 10613719 | Appearance | Powder |
| Formula | C19H18O3 | M.Wt | 294.35 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (4E,6E)-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one | ||
| SMILES | C1=CC(=CC=C1CCC(=O)C=CC=CC2=CC=C(C=C2)O)O | ||
| Standard InChIKey | QIROPQQWKBMABC-ZPUQHVIOSA-N | ||
| Standard InChI | InChI=1S/C19H18O3/c20-17(10-7-16-8-13-19(22)14-9-16)4-2-1-3-15-5-11-18(21)12-6-15/h1-6,8-9,11-14,21-22H,7,10H2/b3-1+,4-2+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The plants of Aframomum letestuianum.
| Description | 1. (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL. |
| Targets | Antifection |
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one Dilution Calculator
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3973 mL | 16.9866 mL | 33.9732 mL | 67.9463 mL | 84.9329 mL |
| 5 mM | 0.6795 mL | 3.3973 mL | 6.7946 mL | 13.5893 mL | 16.9866 mL |
| 10 mM | 0.3397 mL | 1.6987 mL | 3.3973 mL | 6.7946 mL | 8.4933 mL |
| 50 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.3589 mL | 1.6987 mL |
| 100 mM | 0.034 mL | 0.1699 mL | 0.3397 mL | 0.6795 mL | 0.8493 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Trypanocidal diarylheptanoids from Aframomum letestuianum.[Pubmed:12662093]
J Nat Prod. 2003 Mar;66(3):364-7.
Three new diarylheptanoids, (4Z,6E)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-4,6-dien -3-one, letestuianin A (1), (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-4,6-dien-3-one, letestuianin B (2), and 1,7-bis(4-hydroxyphenyl)heptan-3,5-dione, letestuianin C (3), as well as the known (4Z,6E)-5-hydroxy-1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one (5) were isolated from Aframomum letestuianum. The known flavonoids 3-acetoxy-5,7,4'-trihydroxyflavanone, 3-acetoxy-7-methoxy-5,4'-dihydroxyflavanone, 7-methoxy-3,5,4'-trihydroxyflavone, and 3,3',4',5,7-pentahydroxyflavan were also obtained from this plant. Their structures were determined using a combination of 1D and 2D NMR techniques. The four diarylheptanoids were tested for growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes. IC(50) values in the range of 1-3 microg/mL were found for compounds 3 and 5.
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