Products with Sedative hypnotics bioactivity

Cat.No. Product Name
BCN2636 (-)-Bornyl acetate
Bornyl acetate shows highly active whitening and antioxidant activities, has potential applications in cosmeceutical materials. Bornyl acetate has anti-inflammatory activity, may be developed as a preventive agent for lung inflammatory diseases and osteoarthritis; it also has an antiabortive effect through modulation of immunological balance at maternal-fetal interface.
BCN2681 Homobaldrinal
1. Homobaldrinal has low toxic activity. 2. Homobaldrinal has genotoxic activity in the Salmonella/microsome test and the SOS-chromotest.
BCN2790 Polygalasaponin V
1. Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.
BCN2926 Juncusol
1. Juncusol shows significant activity against MRSA strains. 2. Juncusol can induce caspase-3-mediated cytotoxicity in HT22 cells. 3. Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg.
BCN2927 Dehydroeffusol
1. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. 2. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity, it is a potential drug candidate for anti-gastric cancer neovascularization and anti-gastric cancer therapy. 3. Dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. 4. Dehydroeffusol possesses anxiolytic and sedative properties and does not affect the general movement coordination of mice. 5. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA).

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