Homobaldrinal

CAS# 67910-07-0

Homobaldrinal

Catalog No. BCN2681----Order now to get a substantial discount!

Product Name & Size Price Stock
Homobaldrinal: 5mg Please Inquire In Stock
Homobaldrinal: 10mg Please Inquire In Stock
Homobaldrinal: 20mg Please Inquire Please Inquire
Homobaldrinal: 50mg Please Inquire Please Inquire
Homobaldrinal: 100mg Please Inquire Please Inquire
Homobaldrinal: 200mg Please Inquire Please Inquire
Homobaldrinal: 500mg Please Inquire Please Inquire
Homobaldrinal: 1000mg Please Inquire Please Inquire

Quality Control of Homobaldrinal

Number of papers citing our products

Chemical structure

Homobaldrinal

3D structure

Chemical Properties of Homobaldrinal

Cas No. 67910-07-0 SDF Download SDF
PubChem ID 49999 Appearance Powder
Formula C15H16O4 M.Wt 260.28
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (7-formylcyclopenta[c]pyran-4-yl)methyl 3-methylbutanoate
SMILES CC(C)CC(=O)OCC1=COC=C2C1=CC=C2C=O
Standard InChIKey LTVSLKWNAZKBEX-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H16O4/c1-10(2)5-15(17)19-8-12-7-18-9-14-11(6-16)3-4-13(12)14/h3-4,6-7,9-10H,5,8H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Homobaldrinal

The herbs of Valeriana officinalis L.

Biological Activity of Homobaldrinal

Description1. Homobaldrinal has low toxic activity. 2. Homobaldrinal has genotoxic activity in the Salmonella/microsome test and the SOS-chromotest.

Homobaldrinal Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Homobaldrinal Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Homobaldrinal

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.842 mL 19.2101 mL 38.4202 mL 76.8403 mL 96.0504 mL
5 mM 0.7684 mL 3.842 mL 7.684 mL 15.3681 mL 19.2101 mL
10 mM 0.3842 mL 1.921 mL 3.842 mL 7.684 mL 9.605 mL
50 mM 0.0768 mL 0.3842 mL 0.7684 mL 1.5368 mL 1.921 mL
100 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9605 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Homobaldrinal

Cytotoxic potential of valerian constituents and valerian tinctures.[Pubmed:23195845]

Phytomedicine. 1998 May;5(3):219-25.

Underground parts of three Valeriana species, namely V. officinalis L. s.l., V. wallichii DC. (V. jatamansi Jones), and V. edulis Nutt. ex Torr & Gray ssp. procera (H.B.K.) F. G. Meyer (V. mexicana DC.), are used in phytotherapy because of their mild sedative properties. Characteristic constituents of these species, which are regarded also as the active principles, were tested for cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, using the microculture tetrazolium (MTT) assay. Valepotriates of the diene type (valtrate, isovaltrate and acevaltrate) displayed the highest cytotoxicity, with IC50 values of 1-6 muM, following continuous incubation. The monoene type valepotriates (didrovaltrate and isovaleroxyhydroxydidrovaltrate) were 2- to 3-fold less toxic. Baldrinal and Homobaldrinal, decomposition products of valepotriates, were 10- to 30-fold less toxic than their parent compounds. Isovaltral had a higher cytotoxicity than its parent compound isovaltrate. Valerenic acids (valerenic acid, acetoxyvalerenic acid, hydroxyvalerenic acid and methyl valerenate), which are characteristic for V. officinalis, had a low toxicity with IC(50) values between 100 and 200 muM. Freshly prepared and stored tinctures, prepared from roots and rhizomes of the three valerian species, were analysed for valepotriates, baldrinals and valerenic acids, and also tested for cytotoxicity. There was a clear relationship between the valepotriate contents of the freshly prepared tinctures and their toxicity. Upon storage, valepotriates decomposed, which was reflected in a significant reduction of the cytotoxic effect.

Bacterial mutagenicity of the tranquilizing constituents of Valerianaceae roots.[Pubmed:3511364]

Mutat Res. 1986 Jan-Feb;169(1-2):23-7.

The valepotriates valtrate/isovaltrate and dihydrovaltrate are considered to be the main tranquilizing constituents of drugs derived from the roots of several Valerianaceae. The decomposition products of valtrate and isovaltrate include the metabolites baldrinal and Homobaldrinal, respectively, whereas the decomposition products of dihydrovaltrate do not include baldrinal-like metabolites. Purified valtrate/isovaltrate, dihydrovaltrate, baldrinal and Homobaldrinal were investigated for their genotoxic activity in the Salmonella/microsome test and the SOS-chromotest. The valepotriates developed mutagenic activity in these test systems only in the presence of S9 mix, whereas both baldrinals showed mutagenic effects in both tests with and without metabolic activation.

Keywords:

Homobaldrinal,67910-07-0,Natural Products, buy Homobaldrinal , Homobaldrinal supplier , purchase Homobaldrinal , Homobaldrinal cost , Homobaldrinal manufacturer , order Homobaldrinal , high purity Homobaldrinal

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: