Products with Pro-oxidants bioactivity

Cat.No. Product Name
BCN1227 Theobromine
Theobromine is a xanthine alkaloid widely consumed as stimulants and snacks in coffee and cocoa based foods, it may form the basis for a new class of antitussive drugs. Theobromine has antioxidants and also capable of prooxidant action, it may have therapeutic potential for diabetic nephropathy, by reducing kidney ECM accumulation in diabetic. It can inhibit adenosine receptor A1 (AR1) signaling.
BCN1909 Benzoylecgonine
1. Benzoylecgonine causes oxidative stress. 2. Benzoylecgonine and oxytocin increase myometrial contractility, while atosiban and ritodrine induce myometrial relaxation. 3. Benzoylecgonine, validated methodologies from matrices other than blood that can be obtained in the autopsy room would be useful to the forensic toxicologist in the evaluation of a specific forensic case.
BCN2316 Theaflavin-3-gallate
Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell lung carcinoma, it acts as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. Theaflavin-3-gallate can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation.
BCN3855 Alpha-pinene
Alpha-pinene inhibits the nuclear translocation of NF-kappa B induced by LPS in THP-1 cells, and this effect is partly due to the upregulation of I kappa B alpha expression. Alpha-pinene inhibits early root growth and causes oxidative damage in root tissue through enhanced generation of ROS, as indicated by increased lipid peroxidation, disruption of membrane integrity and elevated antioxidant enzyme levels.
BCN6797 4-(4-Hydroxyphenyl)-2-butanone
Raspberry ketone prevents and improves obesity and fatty liver by increasing norepinephrine-induced lipolysis in white adipocytes, it also can increase the fatty acid oxidation and suppressed lipid accumulation in 3T3-L1 adipocytes. Raspberry ketone has anti-melanogenic activity, it could be used to treat hyperpigmentation. Raspberry ketone enhances the differentiation of C3H10T1/2 stem cells into osteoblasts, and it may promote bone formation by an action unrelated to adipocyte differentiation.

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