Products with Genotoxicity bioactivity

Cat.No. Product Name
BCN2131 Integerrimine
1. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.
2. Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring.
BCN2133 Riddelline
1. Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
BCN2162 alpha-Chaconine
1. Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. 2. The cytotoxic effects of α-Solanine and alpha-Chaconine were observed immediately after incubation and were constant after 30min, suggesting that rapid damage of plasma membrane causes the lethal disorder of metabolism.
BCN2217 Tartrazine
Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.
BCN2222 Sunset yellow
Sunset yellow FCF and Brilliant Blue FCF are used as colorant food additives in many food products, they can have cytotoxic and genotoxic potential, it care must be taken when using these materials as a food additive.

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