Products with Cytotoxic bioactivity

Cat.No. Product Name
BCN6228 Glyasperin A
1. Glyasperin A has cytotoxic properties against P-388 cells, its IC50 values being 6.0 microM.
BCN6251 Garjasmin
1. Garjasmine exhibits weak cytotoxic activity against KB and MCF-7 cell lines.
BCN6271 Colchicine
Colchicine is a tubulin inhibitor, and a microtubule polymerization inhibitor with an IC50 of 3 nM. It prevents amyloidosis in our high-risk population and that it can prevent additional deterioration of renal function in patients with amyloidosis who have proteinuria but not the nephrotic syndrome. Colchicine has anti-mitotic activity, it can be used to treat familial mediterranean fever, and as a lead compound for the generation of potent anti-cancer drugs.
BCN6274 Protodioscin
Protodioscin has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties. It appears to possess aphrodisiac activity probably due to its androgen increasing property, it will be useful in developing health food supplement(s) and/or drug(s) against hyperlipidemia.
BCN6332 Licochalcone A
Licochalcone A is an estrogenic flavanoid extracted from licorice root, showing antimalarial, antileishmanial, anticancer, anti-inflammatory, antibacterial and antiviral activities. It could be a promising strategy in treating osteoporotic weight-bearing bones fractures with defects, and be a useful compound for the development of antibacterial agents for the preservation of foods containing high concentrations of salts and proteases, in which cationic peptides might be less effective.

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