Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6348 | Pseudohypericin |
| Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS. Pseudohypericin can inhibit LPS-stimulated PGE2 and NO in mouse macrophages by potentiating suppressor of cytokine signaling 3 (SOCS3) expression, it has anti-tumor potential. | |
| BCN6350 | Sanggenone C |
| 1. Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB. | |
| BCN6354 | Sennidin A |
| 1. Sennidin A in combination with necrosis inducing drugs/therapies may generate synergetic tumoricidal effects on solid malignancies by means of primary debulking and secondary cleansing process. 2. Sennidin A stimulates glucose incorporation in the phosphatidylinositol 3-kinase (PI3K)- and Akt-dependent in rat adipocytes, but in the IR/IRS1-independent manner. 3. Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 uM. | |
| BCN6356 | Sinensetin |
| Sinensetin is a polymethoxylated flavonoids in citrus fruit, as a novel antiangiogenesis agent, has potential for anti-carcinogenesis, antitumor, and cardiovascular protective activities. Sinensetin has antioxidative effect and has anti-inflammatory by regulating the protein level of inhibitorκB-α, it enhances adipogenesis and lipolysis by increasing cAMP levels in adipocytes. | |
| BCN6457 | Lanatoside C |
| 1. Lanatoside C, a cardiac glycoside, is an anti-arrhythmic agent. 2. Lanatoside C acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells. 3. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71, suggest that lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses. | |
