Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6458 | Isorhynchophylline |
| 1. Isorhynchophylline exerts anticancer and anti-metastatic effects through regulation of multiple signaling cascades in hepatocellular carcinoma cells. 2. Isorhynchophylline exerts neuroprotective effect against Aβ 25-35-induced neurotoxicity in vitro via PI3K/Akt signaling pathway. 3. Isorhynchophylline shows antidepressant-like effects, which are mediated, at least in part, by the inhibition of monoamine oxidases. 4. Isorhynchophylline shows inhibition on angiotensin II-induced proliferation in rat vascular smooth muscle cells. 5. Isorhynchophylline shows anti-inflammatory effects in mouse N9 microglial cells. 6. Isorhynchophylline plays a remarkably preventive role in cardiac arrhythmias through the inhibition of calcium currents in rats and guinea pigs. | |
| BCN6523 | Lysicamine |
| 1. Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. 2. Lysicamine has antileishmanial activity. 3. Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). 4. Lysicamine can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells. | |
| BCN6678 | 29-Nor-20-oxolupeol |
| 1. 29-Nor-20-oxolupeol(3 beta-Hydroxy-30-norlupan-20-one) has growth inhibitory effects on HL-60 cells. | |
| BCN6684 | Khellactone |
| 1. Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. 2. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show notable inhibitory activity against -sensitive strains of with IC(50) values from 1.5 and 2.4 microM. | |
| BCN6711 | Yadanzioside P |
| 1. Yadanzioside P has antileukemic and antitumor activities. | |
