Hedgehog
Hh (Hedgehog) signalling is a evolutionarily conserved pathway that is critical for embryonic development, tissue and organ morphogenesis. Mammalian Hh protein ligands include Sonic Hh, Desert Hh and Indian Hh. Dysfunctions of Hh singalling lead to developmental abnormalities and cancer.
Products for Hedgehog
- Cat.No. Product Name Information
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BCN2964
Cyclopamine Inhibitor of Hedgehog (Hh) signaling
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BCN2975
Jervine
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BCC1090
GANT61GLI antagonist; inhibits Hedgehog (Hh) signaling
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BCC1285
GDC-0449 (Vismodegib)Hedgehog antagonist,potent and selective
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BCC3838
PF-5274857Smo antagonist,potent and selective
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BCC3935
LY2940680Hedgehog/SMO antagonist,inhibits Hh signaling
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BCC3936
JK 184Downstream Hedgehog (Hh) signaling pathway inhibitor; inhibits alcohol dehydrogenase 7
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BCC3937
SANT-2Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
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BCC3938
HPI 1Inhibits Hedgehog signaling
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BCC3939
Ciliobrevin AHedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein
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BCC3940
AY 9944 dihydrochlorideHedgehog Inhibitor
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BCC3941
SANT-1Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
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BCC5441
RU-SKI 43
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BCC6390
SAGActivates the Hedgehog signaling pathway; potent Smoothened receptor agonist
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BCC7136
U 18666AInhibitor of Hedgehog (Hh) signaling. Also inhibits cholesterol synthesis
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BCC7937
20(S)-HydroxycholesterolAllosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation
