SenecivernineCAS# 72755-25-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 72755-25-0 | SDF | Download SDF |
| PubChem ID | 442764 | Appearance | White powder |
| Formula | C18H25NO5 | M.Wt | 335.40 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in chloroform and methan | ||
| SMILES | CC1C(C(C(=O)OCC2=CCN3C2C(CC3)OC(=O)C1=C)(C)O)C | ||
| Standard InChIKey | FLUOSFVUPTUYEX-QHOAOGIMSA-N | ||
| Standard InChI | InChI=1S/C18H25NO5/c1-10-11(2)16(20)24-14-6-8-19-7-5-13(15(14)19)9-23-17(21)18(4,22)12(10)3/h5,10,12,14-15,22H,2,6-9H2,1,3-4H3/t10-,12+,14+,15+,18+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | Mutagenicity of pyrrolizidine alkaloids in the Salmonella typhimurium/mammalian microsome system.[Pubmed: 1370983]Mutat Res. 1992 Feb;281(2):143-7.
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| Structure Identification | J Chromatogr. 1985 Dec 6;349(1):23-9.Determination of pyrrolizidine alkaloids in Senecio inaequidens D.C. by capillary gas chromatography.[Pubmed: 4086643]A study of the toxic pyrrolizidine alkaloids contained in Senecio inaequidens D.C., an infestant species of the Senecio genus, widespread in the North East of Italy, is reported.
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Senecivernine Dilution Calculator
Senecivernine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9815 mL | 14.9076 mL | 29.8151 mL | 59.6303 mL | 74.5379 mL |
| 5 mM | 0.5963 mL | 2.9815 mL | 5.963 mL | 11.9261 mL | 14.9076 mL |
| 10 mM | 0.2982 mL | 1.4908 mL | 2.9815 mL | 5.963 mL | 7.4538 mL |
| 50 mM | 0.0596 mL | 0.2982 mL | 0.5963 mL | 1.1926 mL | 1.4908 mL |
| 100 mM | 0.0298 mL | 0.1491 mL | 0.2982 mL | 0.5963 mL | 0.7454 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Mutagenicity of pyrrolizidine alkaloids in the Salmonella typhimurium/mammalian microsome system.[Pubmed:1370983]
Mutat Res. 1992 Feb;281(2):143-7.
The mutagenicity of a series of pyrrolizidine alkaloids, and of extracts from several Italian Senecio species containing pyrrolizidine alkaloids, including S. inaequidens, S. fuchsii and S. cacaliaster, were tested using the Salmonella typhimurium/mammalian microsome system. Retrorsine, Senecivernine, seneciphylline and the Senecio extracts showed a weakly mutagenic activity.
Determination of pyrrolizidine alkaloids in Senecio inaequidens D.C. by capillary gas chromatography.[Pubmed:4086643]
J Chromatogr. 1985 Dec 6;349(1):23-9.
A study of the toxic pyrrolizidine alkaloids contained in Senecio inaequidens D.C., an infestant species of the Senecio genus, widespread in the North East of Italy, is reported. Five of these compounds, Senecivernine, senecionine, integerrimine, retrorsine and an analogue of retrorsine, were identified by means of capillary gas chromatography and capillary gas chromatography-mass spectrometry.
