RosarinCAS# 84954-93-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 84954-93-8 | SDF | Download SDF |
| PubChem ID | 10320370 | Appearance | White-off-white powder |
| Formula | C20H28O10 | M.Wt | 428.43 |
| Type of Compound | Phenylpropanoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in methanol and water | ||
| Chemical Name | (2R,3S,4S,5R,6R)-2-[[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol | ||
| SMILES | C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)COC3C(C(C(O3)CO)O)O)O)O)O | ||
| Standard InChIKey | IEBFEMIXXHIISM-YZOUKVLTSA-N | ||
| Standard InChI | InChI=1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Rosarin is a natural product from Rhodiola rosea L. |
| In vivo | Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.[Pubmed: 23690847]Evid Based Complement Alternat Med. 2013;2013:514049.
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Rosarin Dilution Calculator
Rosarin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3341 mL | 11.6705 mL | 23.341 mL | 46.6821 mL | 58.3526 mL |
| 5 mM | 0.4668 mL | 2.3341 mL | 4.6682 mL | 9.3364 mL | 11.6705 mL |
| 10 mM | 0.2334 mL | 1.1671 mL | 2.3341 mL | 4.6682 mL | 5.8353 mL |
| 50 mM | 0.0467 mL | 0.2334 mL | 0.4668 mL | 0.9336 mL | 1.1671 mL |
| 100 mM | 0.0233 mL | 0.1167 mL | 0.2334 mL | 0.4668 mL | 0.5835 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.[Pubmed:23690847]
Evid Based Complement Alternat Med. 2013;2013:514049.
To determine the biological activity of Rhodiola rosea, the protein expression of iNOS and proinflammatory cytokines was measured after the activation of murine microglial BV2 cells by LPS under the exposure of constituents of Rhodiola rosea: crude extract, rosin, Rosarin, and salidroside (each 1-50 mu g/mL). The LPS-induced expression of iNOS and cytokines in BV2 cells was suppressed by the constituents of Rhodiola rosea in a concentration-dependent manner. Also the expression of the proinflammatory factors iNOS, IL-1 beta , and TNF- alpha in the kidney and prefrontal cortex of brain in mice was suppressed by the oral administration of Rhodiola rosea crude extract (500 mg/kg). To determine the neuroprotective effect of constituents of Rhodiola rosea, neuronal cells were activated by L-glutamate, and neurotoxicity was analyzed. The L-glutamate-induced neurotoxicity was suppressed by the treatment with rosin but not by Rosarin. The level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with rosin and salidroside. These results indicate that Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.
