Oleuropeic acid

CAS# 5027-76-9

Oleuropeic acid

Catalog No. BCN5611----Order now to get a substantial discount!

Product Name & Size Price Stock
Oleuropeic acid:5mg Please Inquire In Stock
Oleuropeic acid:10mg Please Inquire In Stock
Oleuropeic acid:20mg Please Inquire In Stock
Oleuropeic acid:50mg Please Inquire In Stock

Quality Control of Oleuropeic acid

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Chemical structure

Oleuropeic acid

3D structure

Chemical Properties of Oleuropeic acid

Cas No. 5027-76-9 SDF Download SDF
PubChem ID 188320 Appearance Powder
Formula C10H16O3 M.Wt 184.2
Type of Compound Monoterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4S)-4-(2-hydroxypropan-2-yl)cyclohexene-1-carboxylic acid
SMILES CC(C)(C1CCC(=CC1)C(=O)O)O
Standard InChIKey BFYWJELXORKNFO-MRVPVSSYSA-N
Standard InChI InChI=1S/C10H16O3/c1-10(2,13)8-5-3-7(4-6-8)9(11)12/h3,8,13H,4-6H2,1-2H3,(H,11,12)/t8-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Oleuropeic acid

The leaves of Eucalyptus maideni

Biological Activity of Oleuropeic acid

Description1. (+)-Oleuropeic acid shows potent in vitro antitumor-promoting activity, it also suppresses an in vivo two-stage carcinogenesis induced with nitric oxide and 12-O-tetradecanoyl phorbol 13-acetate (TPA) on mouse skin.

Oleuropeic acid Dilution Calculator

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Oleuropeic acid Molarity Calculator

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Preparing Stock Solutions of Oleuropeic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.4289 mL 27.1444 mL 54.2888 mL 108.5776 mL 135.722 mL
5 mM 1.0858 mL 5.4289 mL 10.8578 mL 21.7155 mL 27.1444 mL
10 mM 0.5429 mL 2.7144 mL 5.4289 mL 10.8578 mL 13.5722 mL
50 mM 0.1086 mL 0.5429 mL 1.0858 mL 2.1716 mL 2.7144 mL
100 mM 0.0543 mL 0.2714 mL 0.5429 mL 1.0858 mL 1.3572 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Oleuropeic acid

Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.[Pubmed:11000030]

J Nat Prod. 2000 Sep;63(9):1253-7.

Three new phenol glycosides acylated with (+)-Oleuropeic acid, cypellocarpins A (1), B (2), and C (3), along with seven known compounds, were isolated from the dried leaves of Eucalyptus cypellocarpa. Structures of the new compounds were determined on the basis of spectroscopic methods, including 2D NMR experiments and chemical degradation. These new compounds and a known related glucoside (7) showed potent in vitro antitumor-promoting activity in a short-term bioassay evaluating the inhibitory effect on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl phorbol 13-acetate (TPA). These compounds also suppressed an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.

Radical-scavenging compounds from olive tree (Olea europaea L.) wood.[Pubmed:24328093]

J Agric Food Chem. 2014 Jan 8;62(1):144-51.

The purpose of this study was to complete knowledge on the chemical composition and radical-scavenging activity of olive tree wood. Two new monoterpene glycosides, (-)-Oleuropeic acid 6'-O-alpha-D-glucopyranosyl ester (6a) and (-)-perillic acid 1'-O-beta-D-primeverosyl ester (8), together with the known compounds (-)-Oleuropeic acid (1), (-)-olivil (2), the aldehydic form of oleuropein aglycone (3), (+)-1-hydroxypinoresinol 1-O-beta-D-glucopyranoside (4), (-)-Oleuropeic acid 1'-O-beta-D-glucopyranosyl ester (5), (-)-Oleuropeic acid 6'-O-beta-D-glucopyranosyl ester (6b), and (-)-olivil 4-O-beta-D-glucopyranoside (7) were isolated from an ethyl acetate extract. The radical scavengers found (2-4 and 7) were detected and isolated with the help of the online HPLC-DAD-DPPH/ABTS technique. Compounds 2-4 and 7 displayed a higher antioxidative effect against the free radical DPPH than the reference BHT and lower than hydroxytyrosol, whereas compounds 1, 5, 6a, 6b, and 8 showed no activity.

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