LP 20 hydrochlorideSelective 5-HT7 ligand CAS# 1386928-34-2 |
Related Products
- Atorvastatin Calcium
Catalog No.:BCC2319
CAS No.:134523-03-8
- Pitavastatin Calcium
Catalog No.:BCC3842
CAS No.:147526-32-7
- Pravastatin sodium
Catalog No.:BCC2321
CAS No.:81131-70-6
- Fluvastatin
Catalog No.:BCC1579
CAS No.:93957-54-1
- Fluvastatin Sodium
Catalog No.:BCC2317
CAS No.:93957-55-2
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1386928-34-2 | SDF | Download SDF |
| PubChem ID | 22001617 | Appearance | Powder |
| Formula | C17H21ClN2O | M.Wt | 304.81 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 50 mM in water and to 100 mM in DMSO | ||
| Chemical Name | 1-[2-(4-methoxyphenyl)phenyl]piperazine;hydrochloride | ||
| SMILES | COC1=CC=C(C=C1)C2=CC=CC=C2N3CCNCC3.Cl | ||
| Standard InChIKey | KXZUJPBDJNUNCN-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H20N2O.ClH/c1-20-15-8-6-14(7-9-15)16-4-2-3-5-17(16)19-12-10-18-11-13-19;/h2-9,18H,10-13H2,1H3;1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Ligand of the 5-HT7 receptor (Ki = 2.6 nM); exhibits agonist and antagonist activity. Displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively). |
LP 20 hydrochloride Dilution Calculator
LP 20 hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.2807 mL | 16.4037 mL | 32.8073 mL | 65.6146 mL | 82.0183 mL |
| 5 mM | 0.6561 mL | 3.2807 mL | 6.5615 mL | 13.1229 mL | 16.4037 mL |
| 10 mM | 0.3281 mL | 1.6404 mL | 3.2807 mL | 6.5615 mL | 8.2018 mL |
| 50 mM | 0.0656 mL | 0.3281 mL | 0.6561 mL | 1.3123 mL | 1.6404 mL |
| 100 mM | 0.0328 mL | 0.164 mL | 0.3281 mL | 0.6561 mL | 0.8202 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Securitinine
Catalog No.:BCN6986
CAS No.:13861-71-7
- (R)-3-Carboxy-4-hydroxyphenylglycine
Catalog No.:BCC6606
CAS No.:13861-03-5
- NKH 477
Catalog No.:BCC7126
CAS No.:138605-00-2
- N3PT
Catalog No.:BCC1782
CAS No.:13860-66-7
- 9-Hydroxycanthin-6-one
Catalog No.:BCN3105
CAS No.:138544-91-9
- Tormentic acid
Catalog No.:BCN6198
CAS No.:13850-16-3
- Pomolic acid
Catalog No.:BCN6197
CAS No.:13849-91-7
- 3-Oxopomolic acid
Catalog No.:BCN3485
CAS No.:13849-90-6
- S-(+)-Marmesin
Catalog No.:BCN8288
CAS No.:13849-08-6
- Ro 31-8220 Mesylate
Catalog No.:BCC4999
CAS No.:138489-18-6
- FK 888
Catalog No.:BCC5907
CAS No.:138449-07-7
- A 1070722
Catalog No.:BCC7933
CAS No.:1384424-80-9
New Products
- Eugenol rutinoside
Catalog No.:BCN6201
CAS No.:138772-01-7
- Fmoc-D-1-Nal-OH
Catalog No.:BCC3284
CAS No.:138774-49-3
- Fmoc-D-2-Nal-OH
Catalog No.:BCC3290
CAS No.:138774-94-4
- Fmoc-N-Me-Ile-OH
Catalog No.:BCC3214
CAS No.:138775-22-1
- Isomangiferolic acid
Catalog No.:BCN4768
CAS No.:13878-92-7
- Fmoc-D-Thr(tBu)-OH
Catalog No.:BCC3555
CAS No.:138797-71-4
- 8'-Oxo-6-hydroxydihydrophaseic acid
Catalog No.:BCN7046
CAS No.:1388075-44-2
- Pasakbumin B
Catalog No.:BCN2991
CAS No.:138809-10-6
- 5'-Methoxyhexahydrocurcumin
Catalog No.:BCN7049
CAS No.:138870-96-9
- 1-Acetylpiperazine
Catalog No.:BCC8448
CAS No.:13889-98-0
- Brinzolamide
Catalog No.:BCC2313
CAS No.:138890-62-7
- Entadamide-A-β-D-glucopyranoside
Catalog No.:BCN8452
CAS No.:138916-58-2
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.[Pubmed:22738316]
J Med Chem. 2012 Jul 26;55(14):6375-80.
Here we report the design, synthesis, and 5-HT(7) receptor affinity of a set of 1-(3-biphenyl)- and 1-(2-biphenyl)piperazines. The effect on 5-HT(7) affinity of various substituents on the second (distal) phenyl ring was analyzed. Several compounds showed 5-HT(7) affinities in the nanomolar range and >100-fold selectivity over 5-HT(1A) and adrenergic alpha(1) receptors. 1-[2-(4-Methoxyphenyl)phenyl]piperazine (9a) showed 5-HT(7) agonist properties in a guinea pig ileum assay but blocked 5-HT-mediated cAMP accumulation in 5-HT(7)-expressing HeLa cells.
LP 20 hydrochloride,1386928-34-2,Natural Products,5-HT Receptor, buy LP 20 hydrochloride , LP 20 hydrochloride supplier , purchase LP 20 hydrochloride , LP 20 hydrochloride cost , LP 20 hydrochloride manufacturer , order LP 20 hydrochloride , high purity LP 20 hydrochloride
