CU CPT 22Selective TLR1/2 inhibitor CAS# 1416324-85-0 |
Related Products
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1416324-85-0 | SDF | Download SDF |
| PubChem ID | 71503400 | Appearance | Powder |
| Formula | C19H22O7 | M.Wt | 362.37 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 125 mg/mL (344.95 mM) H2O : < 0.1 mg/mL (insoluble) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | hexyl 3,4,5-trihydroxy-2-methoxy-6-oxobenzo[7]annulene-8-carboxylate | ||
| SMILES | CCCCCCOC(=O)C1=CC(=O)C(=C2C(=C1)C=C(C(=C2O)O)OC)O | ||
| Standard InChIKey | UBQFTTUFRSSOHE-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H22O7/c1-3-4-5-6-7-26-19(24)12-8-11-10-14(25-2)17(22)18(23)15(11)16(21)13(20)9-12/h8-10,22-23H,3-7H2,1-2H3,(H,20,21) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC50 = 0.58 μM). Exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. Inhibits the release of proinflammatory cytokines TNF-α and IL-1β. |
CU CPT 22 Dilution Calculator
CU CPT 22 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.7596 mL | 13.7981 mL | 27.5961 mL | 55.1922 mL | 68.9903 mL |
| 5 mM | 0.5519 mL | 2.7596 mL | 5.5192 mL | 11.0384 mL | 13.7981 mL |
| 10 mM | 0.276 mL | 1.3798 mL | 2.7596 mL | 5.5192 mL | 6.899 mL |
| 50 mM | 0.0552 mL | 0.276 mL | 0.5519 mL | 1.1038 mL | 1.3798 mL |
| 100 mM | 0.0276 mL | 0.138 mL | 0.276 mL | 0.5519 mL | 0.6899 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Dronedarone
Catalog No.:BCN2176
CAS No.:141626-36-0
- (±)-BI-D
Catalog No.:BCC5537
CAS No.:1416258-16-6
- Dronedarone HCl
Catalog No.:BCC4777
CAS No.:141625-93-6
- Beta-D-glucopyranosyl oleanolate
Catalog No.:BCN6530
CAS No.:14162-53-9
- JW 642
Catalog No.:BCC6324
CAS No.:1416133-89-5
- UNC1215
Catalog No.:BCC2023
CAS No.:1415800-43-9
- Angustin B
Catalog No.:BCN7652
CAS No.:1415795-51-5
- Angustin A
Catalog No.:BCN7651
CAS No.:1415795-50-4
- ST-836 hydrochloride
Catalog No.:BCC1969
CAS No.:1415564-68-9
- PF-543 Citrate
Catalog No.:BCC1855
CAS No.:1415562-83-2
- PF-543
Catalog No.:BCC1854
CAS No.:1415562-82-1
- Crizotinib hydrochloride
Catalog No.:BCC5306
CAS No.:1415560-69-8
New Products
- GR 94800
Catalog No.:BCC5799
CAS No.:141636-65-9
- Ivangustin
Catalog No.:BCN3507
CAS No.:14164-59-1
- Thrombin Receptor Activator for Peptide 5 (TRAP-5)
Catalog No.:BCC1025
CAS No.:141685-53-2
- NPEC-caged-D-AP5
Catalog No.:BCC7895
CAS No.:1416943-27-5
- Galanin (2-29) (rat)
Catalog No.:BCC5763
CAS No.:141696-11-9
- Faropenem daloxate
Catalog No.:BCC1571
CAS No.:141702-36-5
- RI-2
Catalog No.:BCC6424
CAS No.:1417162-36-7
- H-Phe(4-Cl)-OH
Catalog No.:BCC3171
CAS No.:14173-39-8
- H-DL-Phe(4-Cl)-OMe.HCl
Catalog No.:BCC3175
CAS No.:14173-40-1
- Exenatide acetate
Catalog No.:BCN8514
CAS No.:141732-76-5
- MM-102
Catalog No.:BCC4551
CAS No.:1417329-24-8
- SDZ SER 082 fumarate
Catalog No.:BCC6994
CAS No.:1417343-80-6
CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a Ki of 0.41 µM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 µM.
CU CPT 22,1416324-85-0,Natural Products,TLR, buy CU CPT 22 , CU CPT 22 supplier , purchase CU CPT 22 , CU CPT 22 cost , CU CPT 22 manufacturer , order CU CPT 22 , high purity CU CPT 22
