11-Hydroxy-12-methoxyabietatrieneCAS# 16755-54-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 16755-54-7 | SDF | Download SDF |
| PubChem ID | 14827262 | Appearance | Cryst. |
| Formula | C21H32O2 | M.Wt | 316.5 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (4bS,8aS)-3-methoxy-4b,8,8-trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-4-ol | ||
| SMILES | CC(C)C1=C(C(=C2C(=C1)CCC3C2(CCCC3(C)C)C)O)OC | ||
| Standard InChIKey | NCQBQRRNDYBXHO-KKSFZXQISA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 11-Hydroxy-12-methoxyabietatriene is a natural product from Salvia candidissima. |
| In vitro | Diterpenes from Salvia broussonetii transformed roots and their insecticidal activity.[Pubmed: 15969497 ]J Agric Food Chem. 2005 Jun 29;53(13):5200-6.
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11-Hydroxy-12-methoxyabietatriene Dilution Calculator
11-Hydroxy-12-methoxyabietatriene Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1596 mL | 15.7978 mL | 31.5956 mL | 63.1912 mL | 78.9889 mL |
| 5 mM | 0.6319 mL | 3.1596 mL | 6.3191 mL | 12.6382 mL | 15.7978 mL |
| 10 mM | 0.316 mL | 1.5798 mL | 3.1596 mL | 6.3191 mL | 7.8989 mL |
| 50 mM | 0.0632 mL | 0.316 mL | 0.6319 mL | 1.2638 mL | 1.5798 mL |
| 100 mM | 0.0316 mL | 0.158 mL | 0.316 mL | 0.6319 mL | 0.7899 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Diterpenes from Salvia broussonetii transformed roots and their insecticidal activity.[Pubmed:15969497]
J Agric Food Chem. 2005 Jun 29;53(13):5200-6.
The new diterpenes brussonol (1) and iguestol (6alpha,11-dihydroxy-12-methoxy-abieta-8,11,13-triene) (2) with an icetexane and a dehydroabietane skeleton, respectively, have been isolated from hairy root cultures of Salvia broussonetii. Other previously known diterpenes, 7-oxodehydroabietane, 11-Hydroxy-12-methoxyabietatriene, taxodione, inuroyleanol, ferruginol, deoxocarnosol 12-methyl ether, cryptojaponol, pisiferal, sugiol, isomanool, 14-deoxycoleon U, 6alpha-hydroxydemethylcryptojaponol, demethylsalvicanol, and demethylcryptojaponol, were also obtained from these roots. The insect antifeedant and toxic effects of several of these compounds were investigated against the insect pests Spodoptera littoralis and Leptinotarsa decemlineata. Additionally, their comparative cytotoxic effects were tested on insect Sf9 and mammalian CHO cells. Demethylsalvicanol (4) was a moderate antifeedant to L. decemlineata, whereas brussonol (1) was inactive. 14-Deoxycoleon U (15) was the strongest antifeedant, whereas demethylcryptojaponol (11) was toxic to this insect. None of these compounds had antifeedant or negative effects on S. littoralis ingestion or weight gains after oral administration. Demethylcryptojaponol (11) was cytotoxic to mammalian CHO and insect Sf9 cell lines, followed by the icetexane derivative brussonol (1), with moderate cytotoxicity in both cases. The remainder of the test compounds showed a strong selective cytotoxicty to insect Sf9 cells, with demethylsalvicanol (4) being the most active.
