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11-Hydroxy-12-methoxyabietatriene

11-Hydroxy-12-methoxyabietatriene

Catalog No. BCN3253
Size Price Stock
20mg $298 In stock
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Quality Control of 11-Hydroxy-12-methoxyabietatriene

Chemical structure

11-Hydroxy-12-methoxyabietatriene

11-Hydroxy-12-methoxyabietatriene Dilution Calculator

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11-Hydroxy-12-methoxyabietatriene Molarity Calculator

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Chemical Properties of 11-Hydroxy-12-methoxyabietatriene

Cas No. 16755-54-7 SDF Download SDF
SMILES CC(C)c1cc2c(c(c1OC)O)[C@]3(CCCC([C@@H]3CC2)(C)C)C
Standard InChIKey NCQBQRRNDYBXHO-KKSFZXQISA-N
Standard InChI InChI=1S/C21H32O2/c1-13(2)15-12-14-8-9-16-20(3,4)10-7-11-21(16,5)17(14)18(22)19(15)23-6/h12-13,16,22H,7-11H2,1-6H3/t16-,21-/m0/s1
Type of Compound Diterpenoids Appearance Cryst.
Formula C21H32O2 M.Wt 316.5
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of 11-Hydroxy-12-methoxyabietatriene

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1596 mL 15.7978 mL 31.5956 mL 63.1912 mL 78.9889 mL
5 mM 0.6319 mL 3.1596 mL 6.3191 mL 12.6382 mL 15.7978 mL
10 mM 0.316 mL 1.5798 mL 3.1596 mL 6.3191 mL 7.8989 mL
50 mM 0.0632 mL 0.316 mL 0.6319 mL 1.2638 mL 1.5798 mL
100 mM 0.0316 mL 0.158 mL 0.316 mL 0.6319 mL 0.7899 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of 11-Hydroxy-12-methoxyabietatriene

This product is isolated and purified from the herbs of Salvia candidissima

References on 11-Hydroxy-12-methoxyabietatriene

Diterpenes from Salvia broussonetii transformed roots and their insecticidal activity.[Pubmed: 15969497]


The new diterpenes brussonol (1) and iguestol (6alpha,11-dihydroxy-12-methoxy-abieta-8,11,13-triene) (2) with an icetexane and a dehydroabietane skeleton, respectively, have been isolated from hairy root cultures of Salvia broussonetii. Other previously known diterpenes, 7-oxodehydroabietane, 11-hydroxy-12-methoxyabietatriene, taxodione, inuroyleanol, ferruginol, deoxocarnosol 12-methyl ether, cryptojaponol, pisiferal, sugiol, isomanool, 14-deoxycoleon U, 6alpha-hydroxydemethylcryptojaponol, demethylsalvicanol, and demethylcryptojaponol, were also obtained from these roots. The insect antifeedant and toxic effects of several of these compounds were investigated against the insect pests Spodoptera littoralis and Leptinotarsa decemlineata. Additionally, their comparative cytotoxic effects were tested on insect Sf9 and mammalian CHO cells. Demethylsalvicanol (4) was a moderate antifeedant to L. decemlineata, whereas brussonol (1) was inactive. 14-Deoxycoleon U (15) was the strongest antifeedant, whereas demethylcryptojaponol (11) was toxic to this insect. None of these compounds had antifeedant or negative effects on S. littoralis ingestion or weight gains after oral administration. Demethylcryptojaponol (11) was cytotoxic to mammalian CHO and insect Sf9 cell lines, followed by the icetexane derivative brussonol (1), with moderate cytotoxicity in both cases. The remainder of the test compounds showed a strong selective cytotoxicty to insect Sf9 cells, with demethylsalvicanol (4) being the most active.



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