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(3R,4S)-Tofacitinib

(3R,4S)-Tofacitinib

Catalog No. BCC4268
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5mg $2,500.00 Please Inquire
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Quality Control of (3R,4S)-Tofacitinib

Chemical structure

(3R,4S)-Tofacitinib

(3R,4S)-Tofacitinib Dilution Calculator

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(3R,4S)-Tofacitinib Molarity Calculator

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Chemical Properties of (3R,4S)-Tofacitinib

Cas No. 1092578-46-5 SDF Download SDF
Chemical Name 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
SMILES CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
Standard InChIKey UJLAWZDWDVHWOW-AAEUAGOBSA-N
Standard InChI InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m0/s1
Formula C16H20N6O M.Wt 312.37
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of (3R,4S)-Tofacitinib

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2013 mL 16.0067 mL 32.0133 mL 64.0266 mL 80.0333 mL
5 mM 0.6403 mL 3.2013 mL 6.4027 mL 12.8053 mL 16.0067 mL
10 mM 0.3201 mL 1.6007 mL 3.2013 mL 6.4027 mL 8.0033 mL
50 mM 0.064 mL 0.3201 mL 0.6403 mL 1.2805 mL 1.6007 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6403 mL 0.8003 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Background on (3R,4S)-Tofacitinib

Tasocitinib also known as CP690550 is an JAK kinase inhibitor. An IC50 estimated at 0.2 μM for PV patient progenitor cells.

Kewords:

(3R,4S)-Tofacitinib,1092578-46-5,JAK/STAT Signaling,JAK, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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