Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN1835 Equisetin
1. Equisetin has antibacterial activity, the MIC's for Equisetin are 8 ug /mL against Bacillus subtilis, 16 ug /mL against Staphylococcus aureus and Methicillin Resistant Staphylococcus aureus (MRSA). 2. Equisetin specifically inhibits the substrate anion carriers of the mitochondrial inner membrane. 3. Equisetin inhibits the DNP-stimulated ATPase activity of rat liver mitochondria and mitoplasts in a concentration-dependent manner; 50% inhibition is caused by about 8 nmol Equisetin/mg protein.
BCN1836 Erythroskyrin
1. Erythroskyrin is a kind of mycotoxin.
BCN1838 Harzianic acid
1. Harzianic acid is a Trichoderma secondary metabolite. 2. Harzianic acid shows plant growth promotion activity. 3. Harzianic acid has antifungal activity and antibiotic activity against Pythium irregulare, Sclerotinia sclerotiorum, and Rhizoctonia solani.
BCN1840 Janolusimide
1. Janolusimide is a neurotoxin and atropine antagonist.
BCN1841 Lactacystin
1. Lactacystin induces cell death and α-synuclein-positive inclusions in cytoplasm. 2. Lactacystin has diversified killing effects on gastric cancer cells, the mechanism may be related to induce the apoptosis by downregulation of nuclear factor kappa B viability. 3. Lactacystin is a selective UPS inhibitor recently used to destroy dopamine (DA) neurons in animal models of Parkinson's disease (PD); marked differences in the rotational response to apomorphine and l-DOPA suggest different mechanisms of neurodegeneration evoked by Lactacystin and 6-OHDA.
BCN1842 alpha-Lipomycin
1. Alpha-Lipomycin belongs to the classification of hybrid peptide-polyketide natural products. 2. Alpha-Lipomycin is active against gram-positive organisms.
BCN1843 Lydicamycin
1. Lydicamycin is active against Gram-positive bacteria and a certain yeast.
BCN1844 Malonomicin
1. Malonomicin has inhibitory effects on gram-positive organisms.