Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN2090 Ligularine
1. Ligularine and clivorine are two hepatotoxic otonecine-type pyrrolizidine alkaloids.
BCN2091 Ligularizine
1. Ligularizine, ligularidine, and neoligularidine are possibly genotoxic carcinogens.
BCN2092 Madurensine
1. Madurensine and doronenine show moderate cytotoxicity on cancerous U-937 cells (IC(50) values: 47.97 and 29.57 M respectively). 2. Madurensine induces autophagy, which in prolonged circumstances may lead to autophagic cell death.
BCN2096 Caftaric acid
Caftaric acid is an inhibitor of the protein-protein interactions mediated by the Src-family kinases, which has anti-mutagenicity. Caftaric acid is the major dietary polyphenol present in various foods, it before methamphetamine injections can prevent liver toxicity and oxidative stress.
BCN2097 Monocrotaline N-oxide
1. Monocrotaline N-oxide is a phagostimulant for larvae and it stimulates the growth and development of adult male androconial organs called coremata. 2. Monocrotaline N-oxide fed to larvae also affects the courtship behavior of adult males. 3. Monocrotaline N-oxide is an adequate precursor for the production of the courtship pheromone hydroxydanaidal.
BCN2098 Spectabiline
1. Spectabiline, monocrotaline, sarracine, lasiocarpine, 7-angelylheliotridine, heliotrine and senecionine have similar antagonistic potencies against responses to both acetylcholine and histamine. 2. Spectabiline shows tumor-inhibitory properties against one or more test tumors.
BCN2105 Desacetyldoronine
1. Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.
BCN2107 Otosenine
1. D-Otocenine elicites low toxicity, it shows spasmolytic properties .