Products with Hepatotoxicity bioactivity

Cat.No. Product Name
BCN2105 Desacetyldoronine
1. Desacetyldoronine is a hepatotoxic pyrrolizidine alkaloid.
BCN2114 Neopetasitenine
1. Petasitenine and neopetasitenine show strong hepatotoxic activity.
BCN2119 Retrorsine
1. Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. 2. OCT1 mediates the liver-specific uptake of Retrorsine, and plays an important role in Retrorsine-induced hepatotoxicity together with CYP3A4. Consequently, the OCT1 inhibitors could be applied to protect the liver from the toxicity of Retrorsine.
BCN2129 Senecionine
1. Senecionine (SEN) is a representative of the hepatotoxic pyrrolizidine alkaloids.
BCN2130 Senecionine N-oxide
1.Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.

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