Products with Cardioprotective bioactivity

Cat.No. Product Name
BCN3100 Alatamine
1. Alatamine can markedly reduce acute myocardial ischemia (AMI)-induced cardiac injury and cardiac myocyte apoptosis, improve the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA).
BCN3155 Ferruginol
1. Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic activities. 2. Ferruginol has cardioprotective, anti-oxidative and anti-inflammatory activities. 3. Ferruginol has anticancer activity, can induce apoptosis in non-small cell lung cancer (NSCLC) cells. 4. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi.
BCN3211 Delta 5-avenasterol
1. Delta 5-avenasterol has antioxidant activity.
BCN3412 Astringin
1. Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. 2. Astringinin can significantly attenuate proinflammatory responses and hepatic injury after trauma-hemorrhage, the salutary effects of astringinin administration on attenuation of hepatic injury following trauma-hemorrhage are likely due to reduction of pro-inflammatory mediator levels.
BCN3444 Kobophenol A
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells.

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