Products with Antimalaric bioactivity

Cat.No. Product Name
BCN2990 Eurycomanone
Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.
BCN2995 7-Methoxy-beta-carboline-1-propionic acid
1. 7-Methoxy-beta-carboline-1-propionic acid demonstrates significant antimalarial activity as judged by studies conducted with cultured Plasmodium falciparum strains.
BCN3089 Digitolutein
1. Digitolutein, extracted from the stem bark and the roots of Morinda lucida Benth., has inhibition on the growth of Plasmodium falciparum in vitro.
BCN3108 Eurycomalactone
1. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. 2. Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. 3. Eurycomalactone displays antiplasmodial activity against Gombak A isolate.
BCN3126 3-hydroxymorindone
Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity.

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