Products with Anticomplementary bioactivity

Cat.No. Product Name
BCN3796 Chrysoeriol-7-O-glucoside
1. Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system. 2. Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border membrane, apigenin-7-O-d-glucoside can inhibit alpha-amylase activity; they can enhance norepinephrine-induced lipolysis in fat cells.
BCN4097 Soyasapogenol B
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
BCN4547 Uncinatone
1. Uncinatone exhibits inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 12.50 uM. 2. Uncinatone shows inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 87 uM. 3. Uncinatone demonstrates cytotoxic activities against the HL-60 tumour cell line (IC50 < 20 uM). 4. Uncinatone exhibits moderate cytotoxicity, inhibits cell proliferation, and induces cell-cycle G(2)/M phase arrest.
BCN4889 Tiliroside
1. Tribuloside can improve behavior and BrdU immunoreactive cells of depression model rats and possess antidepressant effect. 2. Tribuloside exhibits antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL . 3. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity.4. Tiliroside possesses anti-inflammatory, antioxidant, anti-complement, anti-diabetic, anticarcinogenic and hepatoprotective activities. Tiliroside enhances fatty acid oxidation via the enhancement adiponectin signaling associated with the activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders.
BCN5513 Hederagenin
Hederagenin shows anti-cancer,anti-inflammatory, antidepressant-like ,anticomplementary, and antimutagenic effects, it can evoke hemolysis on the erythrocytes, and has cytotoxic on various tumor cell lines, P-388, L-1210, U-937, HL-60, SNU-5 and HepG2. Hederagenin can inhibit LPS-stimulated expression of iNOS, COX-2, and NF-κB, regulate monoamine neurotransmitters and 5-HTT mRNA expression.

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