Products with Antiangiogenic bioactivity

Cat.No. Product Name
BCN4405 Eupatorin
Eupatorin has antiproliferative and antiangiogenic effects, it emerges as a promising agent in anticancer research.Eupatorin-induced cell death is mediated by both the extrinsic and the intrinsic apoptotic pathways and through a mechanism dependent on reactive oxygen species generation. Eupatorin also has meaningful anti-inflammatory property which may be utilized in the development of novel anti-inflammatory treatments.
BCN4417 Dihydrotanshinone I
Dihydrotanshinone I is a potent inhibitor of the HuR:RNA interaction, it exhibits strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation, and UDP-glucuronosyltransferase (UGT) 1A7. Dihydrotanshinone I has antibacterial, anti-cancer, anti-angiogenic, and cytotoxic activities, it induces caspase and ROS dependent apoptosis and autophagy.
BCN4554 Isolicoflavonol
1. Isolicoflavonol is a potential cancer chemopreventive agent.
BCN4774 Enniatin B
1. Enniatin B can decrease Monocytes' endocytosis ability and an increase of CD71. 2. Enniatin B has anticancer benefits, especially for the treatment of cervical cancer. 3. Enniatin B has extensive hepatic metabolism, that reduces in vivo potential . 4. Enniatin B has antiangiogenic properties, indicated by a strong inhibition of human endothelial cell migration and tube formation.
BCN4871 Bavachinin
Bavachinin is a novel natural pan-PPAR agonist , it shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50 = 0.74 μmol/l, 4.00 μmol/l and 8.07 μmol/l in 293T cells, respectively). Bavachinin possesses anti-asthma, anti-angiogenic , anti-inflammatory, antipyretic and analgesic properties, it also exhibits glucose-lowering properties without inducing weight gain and hepatotoxicity.

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