Products with Anti-proliferation bioactivity

Cat.No. Product Name
BCN4424 Pyrogallol
Pyrogallol is a polyphenol compound, which has anti-fungal, anti-psoriatic, anti-inflammatory, and antiproliferative effects . Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions; it is both a sensitizer, a carcinogenic, and an irritant in female BALB/c mice.
BCN4464 Viscidulin III
Viscidulin III (17.4 microM), wogonin (17.4 microM) and luteolin (18.4 microM) were more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines.
BCN4547 Uncinatone
1. Uncinatone exhibits inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 12.50 uM. 2. Uncinatone shows inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 87 uM. 3. Uncinatone demonstrates cytotoxic activities against the HL-60 tumour cell line (IC50 < 20 uM). 4. Uncinatone exhibits moderate cytotoxicity, inhibits cell proliferation, and induces cell-cycle G(2)/M phase arrest.
BCN4591 Casegravol
1. Casegravol shows antiproliferative activity against human gastric adenocarcinoma (MK-1), human uterus carcinoma (HeLa), and murine melanoma (B16F10) cells.
BCN4638 Isodeoxyelephantopin
1. Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation . 2. Isodeoxyelephantopin enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibiting NF-kappaB activation and NF-kappaB-regulated gene expression.

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