Products with Anti-obesity bioactivity

Cat.No. Product Name
BCN2948 Fucoxanthin
Fucoxanthin shows anti-obesity, antioxidant, anti-inflammatory, chemopreventive and/or chemotherapeutic effects. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Fucoxanthin suppresses the inflammation of endotoxin-induced uveitis by blocking the iNOS and COX-2 protein expression and its anti-inflammatory effect on eye is comparable with the effect of predinisolone used in similar doses.
BCN3174 Mahanimbine
1. Mahanimbine inhibits AChE activity in a dose-dependent manner. 2. Mahanimbine and mangiferin increases the glucose utilization in a dose-dependent manner, can prevent obesity and use in management of diabetes. 3. Mahanimbine can prevent high-fat diet (HFD)-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress. 4. Mahanimbine can lower the absorption of dietary fat resulting in dietary fat excretion.
BCN3308 Leachianone G
1. Leachianone G shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. 2. (+/-)Leachianone G 1b, bearing 8-prenyl and 2',4'-dihydoxyl groups, exhibits potent vasorelaxant and neuroprotective effects. 3. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays. 4. Leachianone G shows potent antiviral activity (IC(50) = 1.6 microg/ml).
BCN3470 (+)-Pteryxin
(+)-Pteryxin has muscle-relaxant props, it also shows hepatoprotective and nitric oxide prodn. inhibitory activity.
BCN3796 Chrysoeriol-7-O-glucoside
1. Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system. 2. Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border membrane, apigenin-7-O-d-glucoside can inhibit alpha-amylase activity; they can enhance norepinephrine-induced lipolysis in fat cells.

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