Products with Anti-myocardial ischemia bioactivity

Cat.No. Product Name
BCN3100 Alatamine
1. Alatamine can markedly reduce acute myocardial ischemia (AMI)-induced cardiac injury and cardiac myocyte apoptosis, improve the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA).
BCN3508 1beta-Hydroxyalantolactone
1. 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD.
BCN4368 Triacetonamine
Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine can improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles.
BCN4789 Osajin
1. Osajin shows antitumor activity in different tumor cell lines. 2. The cardioprotection provided by Osajin treatment results from the suppression of oxidative stress and correlates with the improved ventricular function. 3. Osajin induces apoptosis in human NPC cells through multiple apoptotic pathways, including the extrinsic death receptor pathway, and intrinsic pathways relying on mitochondria and endoplasmic reticulum stress.
BCN4957 Nitidine chloride
Nitidine chloride has protective effects on rats during myocardial ischemia/reperfusion, it also exerts an anti-inflammatory property by inhibiting TNF-α, IL-1β, and IL-6 production in association with reduced NF-κB and MAPK signaling pathways in RAW 264.7 cells. It has inhibitory effects on various tumors, such as renal cancer , breast cancer.

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