Products with Anti-allergy bioactivity

Cat.No. Product Name
BCN1535 9-O-Feruloyl-5,5'-dimethoxylariciresinol
1. (+)-9'-O-trans-Feruloyl-5,5'-dimethoxylariciresinol shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml. 2. (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol can inhibit release of histamine from mast cells, it may have anti-allergic inflammatory effect.
BCN1654 Thunberginol C
1. Thunberginol C shows antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in sensitized guinea pig bronchial muscle, 2. Thunberginol C exhibits antimicrobial activity against oral bacteria.
BCN2191 Adrenaline
L-Epinephrine is a hormone secreted by the medulla of the adrenal glands. L-Epinephrine is an α-adrenergic and β-adrenergic receptor agonist.Epinephrine-MC RDSTs facilitated a twofold increase in epinephrine absorption and a 50% reduction in the sublingual dose, this novel sublingual tablet formulation is potentially useful for the first-aid treatment of anaphylaxis in community settings. Pre-hospital administration of Adrenaline by emergency medical services improves the long term outcome in patients with out of hospital cardiac arrest, although the absolute increase of neurologically intact survival was minimal.
BCN2271 Gomisin N
Gomisin N has anti-oxdiant, anti-inflammatory, anti-cancer and anti-hepatitis activities; it produces beneficial sedative and hypnotic bioactivity, which may be mediated by the modification of the serotonergic and GABAergic system. Gomisin N can enhance TNF-α-induced apoptosis by suppressing of NF-κB and EGFR signaling pathways, and potentiate TRAIL-induced apoptosis through ROS-mediated up-regulation of death receptors 4 and 5.
BCN2294 Sophoricoside
Sophoricoside has anti-inflammatory, anti-cancer, anti-bone loss, and immunosuppressive effects. Sophoricoside is an effective regulator of lipogenesis and glucose consumption and may find utility in the treatment of obesity and type 2 diabetes. Sophoricoside exposure reduced the number of implanted embryos in a dose-dependent manner and failed the embryo implantation through altering the morphology of uterine and compromising the endometrial receptivity.

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