Products with Analgesia bioactivity

Cat.No. Product Name
BCN5217 Corydalmine
1. Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. 2. 1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. 3. l-Corydalmine exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent.
BCN5226 Sideroxylin
1. Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump.
BCN5228 gamma-Mangostin
gamma-Mangostin is a dual agonist that activates both PPARδ and PPARα, is also a novel competitive antagonist for the 5-HT2A receptors in vascular smooth muscles and platelets.gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells, and exhibits antihypertensive, anti-inflammatory, analgesic effects. gamma-Mangostin could as a preventive agent of the metabolic syndrome, and could serve as a micronutrient for colon cancer prevention.
BCN5259 Hypophyllanthin
1. Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice. 2. Hypophyllanthin can modulate the vascular tension via the endothelium-independent mechanisms. 3. Hypophyllanthin can directly inhibit P-gp activity and does not interfere with MRP2 activity, it may reversibly inhibit P-gp function. 4. Hypophyllanthin offers a promising means for treatment of chronic muscle pain. 5. Hypophyllanthin has estrogenic properties against carbofuran induced toxicity in female rats.
BCN5318 3'-O-Methylorobol
1. 3'-O-Methylorobol can increase osteoblast differentiation. 2. 3'-O-Methylorobol exerts potential analgesic properties. 3. 3'-O-Methylorobol exhibites moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay.

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