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Trillenoside A

CAS# 58809-09-9

Trillenoside A

Catalog No. BCN6387----Order now to get a substantial discount!

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Trillenoside A: 5mg Please Inquire In Stock
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Quality Control of Trillenoside A

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Chemical structure

Trillenoside A

3D structure

Chemical Properties of Trillenoside A

Cas No. 58809-09-9 SDF Download SDF
PubChem ID 102060368 Appearance Powder
Formula C47H70O24 M.Wt 1019.05
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1~{R},3'~{S},4~{R},4'~{R},5'~{S},6~{S},7~{R},8~{R},12~{S},13~{R},14~{R},16~{R})-14-[(2~{S},3~{R},4~{S},5~{S})-3-[(2~{S},3~{R},4~{R},5~{S},6~{S})-4-[(2~{S},3~{R},4~{R})-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-4-[(2~{S},3~{R},4~{S},5~{R})-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3',4',16-trihydroxy-7-(hydroxymethyl)-5',13-dimethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-2(9),18-diene-6,2'-oxane]-3-one
SMILES CC1COC2(C(C3C(O2)C(=O)C4=C3CCC5C4CC=C6C5(C(CC(C6)O)OC7C(C(C(CO7)O)OC8C(C(C(CO8)O)O)O)OC9C(C(C(C(O9)C)O)OC2C(C(CO2)(CO)O)O)O)C)CO)C(C1O)O
Standard InChIKey DDFDNHCZISHVDX-UTWIKJIVSA-N
Standard InChI InChI=1S/C47H70O24/c1-16-11-65-47(39(59)29(16)53)23(10-48)28-21-6-7-22-20(27(21)32(56)36(28)71-47)5-4-18-8-19(50)9-26(45(18,22)3)67-43-38(35(25(52)13-63-43)68-41-33(57)31(55)24(51)12-62-41)70-42-34(58)37(30(54)17(2)66-42)69-44-40(60)46(61,14-49)15-64-44/h4,16-17,19-20,22-26,28-31,33-44,48-55,57-61H,5-15H2,1-3H3/t16-,17-,19+,20+,22-,23-,24+,25-,26+,28-,29+,30-,31-,33+,34+,35-,36+,37+,38+,39-,40-,41-,42-,43-,44-,45-,46+,47-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Trillenoside A

The herbs of Trillium tschonoskii Maxim.

Biological Activity of Trillenoside A

Description1. Saponin V (300,150,75 mg·kg-1) can significantly decrease the times of cough, saponin V 300 mg/kg can remarkably increase cough latent period, saponin V 5 g/L remarkably antagonized contraction of isolated ileum, saponin V 2.5 and 1.25 g/L antagonized trachea spasm in guinea pig induced by histamine; saponin V exhibits significant antitussive, expectorant and antispasmodic effects. 2. Chikusetsu saponin V can attenuate H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells through Sirt1/PGC-1α/Mn-SOD signaling pathways, suggests that chikusetsu saponin V exhibits neuroprotective effects.
TargetsBcl-2/Bax | Sirtuin | SOD | ROS

Trillenoside A Dilution Calculator

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Trillenoside A Molarity Calculator

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Preparing Stock Solutions of Trillenoside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.9813 mL 4.9065 mL 9.8131 mL 19.6261 mL 24.5327 mL
5 mM 0.1963 mL 0.9813 mL 1.9626 mL 3.9252 mL 4.9065 mL
10 mM 0.0981 mL 0.4907 mL 0.9813 mL 1.9626 mL 2.4533 mL
50 mM 0.0196 mL 0.0981 mL 0.1963 mL 0.3925 mL 0.4907 mL
100 mM 0.0098 mL 0.0491 mL 0.0981 mL 0.1963 mL 0.2453 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Trillenoside A

An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii.[Pubmed:17409572]

Chem Pharm Bull (Tokyo). 2007 Apr;55(4):679-81.

A novel 18-norspirostanol saponin (1), along with Trillenoside A (2), was obtained from the underground parts of Trillium tschonoskii MAXIM., collected in Shennongjia Forest District, China. Based on the chemical and spectroscopic evidences, their structures were determined as shown in Fig. 1. 1 and 2 displayed marked inhibitory action towards COX-2 production in macrophagocytes of the mouse abdominal cavity stimulated by LPS at 10 microg/ml.

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