Myzodendrone

CAS# 101705-37-7

Myzodendrone

Catalog No. BCN7257----Order now to get a substantial discount!

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Quality Control of Myzodendrone

Number of papers citing our products

Chemical structure

Myzodendrone

3D structure

Chemical Properties of Myzodendrone

Cas No. 101705-37-7 SDF Download SDF
PubChem ID 181027 Appearance Powder
Formula C16H22O8 M.Wt 342.34
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[4-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]butan-2-one
SMILES CC(=O)CCC1=CC(=C(C=C1)O)OC2C(C(C(C(O2)CO)O)O)O
Standard InChIKey LMPCSMHAJDXHSV-IBEHDNSVSA-N
Standard InChI InChI=1S/C16H22O8/c1-8(18)2-3-9-4-5-10(19)11(6-9)23-16-15(22)14(21)13(20)12(7-17)24-16/h4-6,12-17,19-22H,2-3,7H2,1H3/t12-,13-,14+,15-,16-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Myzodendrone

The flowering stems of Vitex agnus-castus.

Biological Activity of Myzodendrone

Description1. Myzodendrone is a highly effective as free radical scavenger.

Myzodendrone Dilution Calculator

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Myzodendrone Molarity Calculator

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Preparing Stock Solutions of Myzodendrone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9211 mL 14.6054 mL 29.2107 mL 58.4215 mL 73.0268 mL
5 mM 0.5842 mL 2.9211 mL 5.8421 mL 11.6843 mL 14.6054 mL
10 mM 0.2921 mL 1.4605 mL 2.9211 mL 5.8421 mL 7.3027 mL
50 mM 0.0584 mL 0.2921 mL 0.5842 mL 1.1684 mL 1.4605 mL
100 mM 0.0292 mL 0.1461 mL 0.2921 mL 0.5842 mL 0.7303 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Myzodendrone

Antioxidant and free radical scavenging activities of Misodendrum punctulatum, myzodendrone and structurally related phenols.[Pubmed:16372370]

Phytother Res. 2005 Dec;19(12):1043-7.

The peroxyl radical scavenging activity of a dry methanol extract of Misodendrum punctulatum was determined by means of luminol-enhanced chemiluminescence assay, allowing to calculate the total reactive antioxidant potential (TRAP) index equal to 239 +/- 26 microm, expressed in Trolox equivalents. The flavan-3-ol catechin (1) and the phenylbutanone derivative Myzodendrone (2) were identified through assay-guided fractionation as active metabolites present in the extract, and their structures were elucidated by chemical and spectroscopic analysis. Three other structurally related synthetic phenols, dehydrozingerone (3), zingerone (4) and Myzodendrone aglycone (5), were also analysed using this method. Compounds 1 and 2 were highly effective as free radical scavengers (TRAP = 1257 microm and 1018 microm, respectively) when compared with Trolox (TRAP = 144 microm), used as a standard. Compounds 3 and 5 were also active showing TRAP values of 229 microm and 219 microm, respectively, similarly to that observed for the dry extract. On the other hand, 4 was inactive. Catechin (1) also reduced the production of thiobarbituric acid reactive substances (TBARS) in rat liver homogenates, with IC50 = 26 microg/mL, superior to that obtained for Trolox, IC50 = 73 microg/mL. Compounds 2 and 5 showed IC50 values > 1000 microg/mL, while no activity could be observed for 3, 4, or the extract.

Glucosides from Vitex agnus-castus.[Pubmed:12895546]

Phytochemistry. 2003 Aug;63(8):959-64.

The methanolic extract of the flowering stems of Vitex agnus-castus yielded three new iridoids: 6'-O-foliamenthoylmussaenosidic acid (agnucastoside A), 6'-O-(6,7-dihydrofoliamenthoyl)mussaenosidic acid (agnucastoside B) and 7-O-trans-p-coumaroyl-6'-O-trans-caffeoyl-8-epiloganic acid (agnucastoside C) in addition to four known iridoids (aucubin, agnuside, mussaenosidic acid and 6'-O-p-hydroxybenzoylmussaenosidic acid) and one known phenylbutanone glucoside (Myzodendrone). The structure elucidations were mainly done by spectroscopic methods (1D and 2D NMR spectra) and MS data interpretation. The purified compounds were tested for biological activities against various microorganisms and cancer cell lines.

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