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Methylnissolin-3-O-glucoside

CAS# 94367-42-7

Methylnissolin-3-O-glucoside

Catalog No. BCN3829----Order now to get a substantial discount!

Product Name & Size Price Stock
Methylnissolin-3-O-glucoside:10mg $324.00 In stock
Methylnissolin-3-O-glucoside:20mg $551.00 In stock
Methylnissolin-3-O-glucoside:50mg $1296.00 In stock
Methylnissolin-3-O-glucoside:100mg $2268.00 In stock
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Quality Control of Methylnissolin-3-O-glucoside

Quality Control & MSDS

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Chemical structure

Methylnissolin-3-O-glucoside

3D structure

Chemical Properties of Methylnissolin-3-O-glucoside

Cas No. 94367-42-7 SDF Download SDF
PubChem ID 101679160 Appearance Powder
Formula C23H26O10 M.Wt 462.5
Type of Compound Phenols Storage Desiccate at -20°C
Synonyms 9,10-Dimethoxypterocarpan 3-glucoside
Solubility Soluble in methanol and pyridine
Chemical Name (2S,3R,4S,5S,6R)-2-[[(6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES COC1=C(C2=C(C=C1)C3COC4=C(C3O2)C=CC(=C4)OC5C(C(C(C(O5)CO)O)O)O)OC
Standard InChIKey PCIXSTFFMHVOMF-PBGSHFJYSA-N
Standard InChI InChI=1S/C23H26O10/c1-28-14-6-5-11-13-9-30-15-7-10(3-4-12(15)20(13)33-21(11)22(14)29-2)31-23-19(27)18(26)17(25)16(8-24)32-23/h3-7,13,16-20,23-27H,8-9H2,1-2H3/t13-,16+,17+,18-,19+,20-,23+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Methylnissolin-3-O-glucoside

The herbs of Astragalus sinicus L.

Biological Activity of Methylnissolin-3-O-glucoside

Description(6aR,11aR)-9,10-Dimethoxypterocarpan 3-O-β-D-glucoside(Methylnissolin-3-O- glucoside) has antioxidant activity.
In vitro

Study on Scavenging Activities for Superoxide Anion Radicals and Structure-Activity Relationship of Flavonoids from Astragalus membranaceus(Fish.) Bge. var.mongholicus(Bge.) Hsiao[Reference: WebLink]

Chinese Pharmaceutical Journal, 2008, 43(4):256+257-259.

To study the scavenging activities of the flavonoids for superoxide anion radicals from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, and to analyze the structure-activity relationship of the compounds.
METHODS AND RESULTS:
The flavonoids were isolated from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, Their antioxidant activities were compared by scavenging the superoxide anion radicals generated by the Pyrogallic acid 3-Amino-Phthalhy-drazid(Luminol)-Na2CO 3/NaHCO3 buffer (pH 10.2) system. Twelve compounds were isolated from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao, they were quercetin(I), isoquercitrin(II), rutin(III), kaempferol(IV), isorhamnetin(V), formononetin(VI), formononetin-7-O-β-D- glucoside(VII), calycosin(VIII), (3R) 8,2′-dihydroxy-7,4′- dimethoxyisoflavan(IX), 2′,4′-dimethoxy-3′-hydroxyisoflavan-6- O-β-glucopyranoside(X), (6aR,11aR) 3,9-dimethoxy-10-hydroxypterocarpan(XI) and (6aR,11aR) 9,10-dimethoxypterocarpan-3-O-β-D-glucoside(Methylnissolin-3-O-glucoside,XII). The concentration effect relationships were all logarithmic (y = alogx + b) over the range of 10%-90% of the scavenging activities. The scavenging activities of the flavonoids for superoxide anion were decided by their structures.
CONCLUSIONS:
The flavonoids from Astragalus membranaceus (Fish.) Bge. var. mongholicus (Bge.) Hsiao have strong scavenging activities of the superoxide anion, and they are the main antioxidants in the herb.

Methylnissolin-3-O-glucoside Dilution Calculator

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Methylnissolin-3-O-glucoside Molarity Calculator

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Preparing Stock Solutions of Methylnissolin-3-O-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1622 mL 10.8108 mL 21.6216 mL 43.2432 mL 54.0541 mL
5 mM 0.4324 mL 2.1622 mL 4.3243 mL 8.6486 mL 10.8108 mL
10 mM 0.2162 mL 1.0811 mL 2.1622 mL 4.3243 mL 5.4054 mL
50 mM 0.0432 mL 0.2162 mL 0.4324 mL 0.8649 mL 1.0811 mL
100 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.4324 mL 0.5405 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Methylnissolin-3-O-glucoside (Methylnissolin-3-O-β-D-glucoside) is a flavonoid from the roots of Astragalus membranaceus with anti-inflammatory effects.

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