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Melliferone

CAS# 377724-68-0

Melliferone

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Product Name & Size Price Stock
Melliferone:5mg $308 In stock

Quality Control of Melliferone

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Chemical structure

Melliferone

3D structure

Chemical Properties of Melliferone

Cas No. 377724-68-0 SDF Download SDF
PubChem ID 489940 Appearance Powder
Formula C30H44O3 M.Wt 452.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,4S,5R,8R,13S,14R,17S,18R)-4,5,9,9,13,20,20-heptamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-ene-10,23-dione
SMILES CC1(CCC23CCC4(C5(CCC6C(C(=O)CCC6(C5C=CC4(C2C1)OC3=O)C)(C)C)C)C)C
Standard InChIKey BHVMSBIGWPPGBF-LHAYROSJSA-N
Standard InChI InChI=1S/C30H44O3/c1-24(2)14-16-29-17-15-28(7)27(6)12-8-19-25(3,4)22(31)10-11-26(19,5)20(27)9-13-30(28,21(29)18-24)33-23(29)32/h9,13,19-21H,8,10-12,14-18H2,1-7H3/t19-,20+,21+,26-,27+,28-,29-,30-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Melliferone

The fruits of Liquidambar formosana Hance

Melliferone Dilution Calculator

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Melliferone Molarity Calculator

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Preparing Stock Solutions of Melliferone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.209 mL 11.0448 mL 22.0897 mL 44.1794 mL 55.2242 mL
5 mM 0.4418 mL 2.209 mL 4.4179 mL 8.8359 mL 11.0448 mL
10 mM 0.2209 mL 1.1045 mL 2.209 mL 4.4179 mL 5.5224 mL
50 mM 0.0442 mL 0.2209 mL 0.4418 mL 0.8836 mL 1.1045 mL
100 mM 0.0221 mL 0.1104 mL 0.2209 mL 0.4418 mL 0.5522 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Melliferone

Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis.[Pubmed:11678650]

J Nat Prod. 2001 Oct;64(10):1278-81.

A new triterpenoid named Melliferone (1), three known triterpenoids, moronic acid (2), anwuweizonic acid (3), and betulonic acid (4), and four known aromatic compounds (5-8) were isolated from Brazilian propolis and tested for anti-HIV activity in H9 lymphocytes. Moronic acid (2) showed significant anti-HIV activity (EC(50) <0.1 microg/mL, TI >186) and was modified to develop more potent anti-AIDS agents.

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