Macamide B

CAS# 74058-71-2

Macamide B

Catalog No. BCN1366----Order now to get a substantial discount!

Product Name & Size Price Stock
Macamide B:5mg $74.00 In Stock
Macamide B:10mg Please Inquire Instock
Macamide B:20mg Please Inquire Instock
Macamide B:50mg Please Inquire Instock
Molarity Calculator Dilution Calculator Send Mail Directly

Quality Control of Macamide B

Quality Control & MSDS

Number of papers citing our products

Chemical structure

Macamide B

3D structure

Chemical Properties of Macamide B

Cas No. 74058-71-2 SDF Download SDF
PubChem ID 11198769 Appearance Powder
Formula C23H39NO M.Wt 345.6
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name N-benzylhexadecanamide
SMILES CCCCCCCCCCCCCCCC(=O)NCC1=CC=CC=C1
Standard InChIKey MLGPKWUKOQAAGI-UHFFFAOYSA-N
Standard InChI InChI=1S/C23H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-23(25)24-21-22-18-15-14-16-19-22/h14-16,18-19H,2-13,17,20-21H2,1H3,(H,24,25)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Macamide B

The herbs of Lepidium meyenii Walp

Biological Activity of Macamide B

In vitro

Two macamide extracts relieve physical fatigue by attenuating muscle damage in mice.[Reference: WebLink]

Journal of the Science of Food and Agriculture, 2019,99(3):1405-1412.

Macamides, the main active component contained in maca, have attracted increasing attention due to their various bioactivities.
METHODS AND RESULTS:
In this study, crude macamides extract (CME) and purified macamides extract (PME) were prepared by enzyme‐assisted extraction and macroporous resin separation, and anti‐fatigue effects of CME and PME were evaluated in a forced swimming model. The composition analysis results revealed that both CME and PME mainly contain 8 kinds of macamides. Based on the results of weight‐loaded forced swimming test, compared with control group, CME and and PME groups could prolong the exhaustive swimming time, increase the levels of liver glycogen (LG) and muscle glycogen (MG), accelerate the fatty acids oxidation in serum to provide energy, eliminate the accumulation of blood lactic acid (BLA) and blood urea nitrogen (BUN), as well as decrease the serum biomarkers for muscle damage, such as lactate dehydrogenase (LDH) and creatine kinase (CK). In addition, histological analysis indicated that CME and PME attenuated damage of skeletal muscle and myocardium in mice during exercise.
CONCLUSIONS:
Two macamides extracts have a beneficial effect on relieving physical fatigue by attenuating the damage of skeletal muscle and myocardium during exercise, and a better effect was observed in PME group.

Macamide B Dilution Calculator

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Macamide B Molarity Calculator

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Preparing Stock Solutions of Macamide B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8935 mL 14.4676 mL 28.9352 mL 57.8704 mL 72.338 mL
5 mM 0.5787 mL 2.8935 mL 5.787 mL 11.5741 mL 14.4676 mL
10 mM 0.2894 mL 1.4468 mL 2.8935 mL 5.787 mL 7.2338 mL
50 mM 0.0579 mL 0.2894 mL 0.5787 mL 1.1574 mL 1.4468 mL
100 mM 0.0289 mL 0.1447 mL 0.2894 mL 0.5787 mL 0.7234 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).

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