Goniodiol

CAS# 96422-52-5

Goniodiol

Catalog No. BCN3958----Order now to get a substantial discount!

Product Name & Size Price Stock
Goniodiol: 5mg $725 In Stock
Goniodiol: 10mg Please Inquire In Stock
Goniodiol: 20mg Please Inquire Please Inquire
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Quality Control of Goniodiol

Number of papers citing our products

Chemical structure

Goniodiol

3D structure

Chemical Properties of Goniodiol

Cas No. 96422-52-5 SDF Download SDF
PubChem ID 180702 Appearance Oil
Formula C13H14O4 M.Wt 234.3
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-2-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-2,3-dihydropyran-6-one
SMILES C1C=CC(=O)OC1C(C(C2=CC=CC=C2)O)O
Standard InChIKey RTNQVKQMVIXUPZ-RTXFEEFZSA-N
Standard InChI InChI=1S/C13H14O4/c14-11-8-4-7-10(17-11)13(16)12(15)9-5-2-1-3-6-9/h1-6,8,10,12-13,15-16H,7H2/t10-,12-,13+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Goniodiol

The herbs of Goniothalamus yunnanensis

Biological Activity of Goniodiol

Description1. (+)-Goniodiol and 7-epi-(+)-Goniodiol show high antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia.
TargetsAntifection

Goniodiol Dilution Calculator

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Goniodiol Molarity Calculator

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Preparing Stock Solutions of Goniodiol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Goniodiol

A highly enantioselective total synthesis of (+)-goniodiol.[Pubmed:16633562]

Org Biomol Chem. 2006 May 7;4(9):1698-706.

A high-yielding enantioselective total synthesis of the bioactive styryllactone (+)-Goniodiol has been realised, starting from readily available (S)-glycidol. A key step is an oxygen-to-carbon rearrangement of a silyl enol ether linked via an anomeric centre, facilitating the rapid and diastereoselective construction of this functionalised system.

Stereoselective syntheses of (+)-goniodiol, (-)-8-epigoniodiol, and (+)-9-deoxygoniopypyrone via alkoxyallylboration and ring-closing metathesis.[Pubmed:12375995]

J Org Chem. 2002 Oct 18;67(21):7547-50.

A convenient synthesis of (+)-Goniodiol, (-)-8-epiGoniodiol, and (+)-9-deoxygoniopypyrone has been developed via asymmetric alkoxyallylboration and ring-closing metathesis pathways.

Syntheses of all stereoisomers of goniodiol from yeast-reduction products and their antimicrobiological activity.[Pubmed:18776681]

Biosci Biotechnol Biochem. 2008 Sep;72(9):2342-52.

All stereoisomers of Goniodiol were synthesized from yeast-reduction products. The C-6 chiral centers were converted from the chiral centers of the yeast-reduction products. Stereoselective conversion of the alkene, which had been prepared from the yeast-reduction product, to glycol constructed the C-7 and C-8 stereochemistry. (+)-Goniodiol and 7-epi-(+)-Goniodiol showed the highest antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia.

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