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Daidzein-4',7-diglucoside

CAS# 53681-67-7

Daidzein-4',7-diglucoside

Catalog No. BCN8135----Order now to get a substantial discount!

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Daidzein-4',7-diglucoside: 5mg $173 In Stock
Daidzein-4',7-diglucoside: 10mg Please Inquire In Stock
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Quality Control of Daidzein-4',7-diglucoside

Number of papers citing our products

Chemical structure

Daidzein-4',7-diglucoside

3D structure

Chemical Properties of Daidzein-4',7-diglucoside

Cas No. 53681-67-7 SDF Download SDF
PubChem ID 171292 Appearance Powder
Formula C27H30O14 M.Wt 578.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-[(2~{S},3~{R},4~{S},5~{S},6~{R})-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[4-[(2~{S},3~{R},4~{S},5~{S},6~{R})-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
SMILES C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O)OC5C(C(C(C(O5)CO)O)O)O
Standard InChIKey VWEWSCDQMVNOJP-IPOZFMEPSA-N
Standard InChI InChI=1S/C27H30O14/c28-8-17-20(31)22(33)24(35)26(40-17)38-12-3-1-11(2-4-12)15-10-37-16-7-13(5-6-14(16)19(15)30)39-27-25(36)23(34)21(32)18(9-29)41-27/h1-7,10,17-18,20-29,31-36H,8-9H2/t17-,18-,20-,21-,22+,23+,24-,25-,26-,27-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Daidzein-4',7-diglucoside

The roots of Pueraria lobata (Willd.) Ohwi.

Protocol of Daidzein-4',7-diglucoside

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(8):1040-2.

Chemical constituents of Ammopiptanthus mongolicus.[Pubmed: 21809581]

To study the chemical constituents of aerial parts of Ammopiptanthus mongolicus.
METHODS AND RESULTS:
Isolation and purification were carried out on silica gel,Sephadex LH-20 and HPLC column chromatography.The structures of the compounds were identified by physico-chemical properties and spectral analysis. Nine compounds were isolated and identified as(+)-maackiain(1),brevifolin(2),7-hydroxy-4′-methoxy isoflavanone(3),Daidzein-4',7-diglucoside(4),genistein 4′,7-di-O-β-D-glucoside(5),isolupalbigenin(6),ononin(7),β-sitosterol(8),β-daucosterol(9).
CONCLUSIONS:
Compounds 2,4~6 were obtained from the genus Ammopiptanthus for the first time.

Daidzein-4',7-diglucoside Dilution Calculator

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Daidzein-4',7-diglucoside Molarity Calculator

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Preparing Stock Solutions of Daidzein-4',7-diglucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7286 mL 8.643 mL 17.2861 mL 34.5722 mL 43.2152 mL
5 mM 0.3457 mL 1.7286 mL 3.4572 mL 6.9144 mL 8.643 mL
10 mM 0.1729 mL 0.8643 mL 1.7286 mL 3.4572 mL 4.3215 mL
50 mM 0.0346 mL 0.1729 mL 0.3457 mL 0.6914 mL 0.8643 mL
100 mM 0.0173 mL 0.0864 mL 0.1729 mL 0.3457 mL 0.4322 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Daidzein-4',7-diglucoside

Potentiation of the bioavailability of daidzin by an extract of Radix puerariae.[Pubmed:8633056]

Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4284-8.

The dose effect of pure daidzin on the suppression of ethanol intake in Syrian golden hamsters was compared with that of crude daidzin contained in a methanol extract of Radix puerariae (RP). EC50 values estimated from the graded dose-response curves for pure daidzin and RP extract daidzin are 23 and 2.3 mg per hamster per day, respectively. Apparently the antidipsotropic activity of the RP extract cannot be accounted for solely by its daidzin content (22 mg/g). In addition to daidzin, six other isoflavones were identified in the RP extract and quantified--namely, puerarin (160 mg per g of extract), genistin (3.7 mg/g), daidzein (2.6 mg/g), daidzein-4',7-diglucoside (1.2 mg/g), genistein (0.2 mg/g), and formononetin (0.16 mg/g). None of these, administered either alone or combined, contributes in any significant way to the antidipsotropic activity of the extract. Plasma daidzin concentration-time curves determined in hamsters administered various doses of pure daidzin or RP extract by i.p.injection indicate that the crude extract daidzin has approximately 10 times greater bioavailability than the pure compound. Reconstruction of the dose-response effects for pure and crude daidzin using bioavailable daidzin rather than administered dose gives a single curve. Synthetic daidzin added to the RP extract acquires the bioavailability of the endogenous daidzin that exists naturally in the extract. These results show that (i) daidzin is the major active principle in methanol extracts of RP, and (ii) additional constituents in the methanol extract of RP assist uptake of daidzin in golden hamsters.

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